Department of Physics, HUCH Cancer Center, Helsinki University Central Hospital, Helsinki, Finland.
J Synchrotron Radiat. 2011 Sep;18(Pt 5):689-96. doi: 10.1107/S090904951102810X. Epub 2011 Jul 26.
High-resolution analyser-based X-ray imaging computed tomography (HR ABI-CT) findings on in vitro human breast cancer are compared with histopathology, mammography, computed tomography (CT) and magnetic resonance imaging. The HR ABI-CT images provided significantly better low-contrast visibility compared with the standard radiological images. Fine cancer structures indistinguishable and superimposed in mammograms were seen, and could be matched with the histopathological results. The mean glandular dose was less than 1 mGy in mammography and 12-13 mGy in CT and ABI-CT. The excellent visibility of in vitro breast cancer suggests that HR ABI-CT may have a valuable role in the future as an adjunct or even alternative to current breast diagnostics, when radiation dose is further decreased, and compact synchrotron radiation sources become available.
高分辨率分析器基 X 射线成像计算机断层扫描（HR ABI-CT）在体外人乳腺癌的影像学表现与组织病理学、乳房 X 线摄影术、计算机断层扫描（CT）和磁共振成像进行比较。与标准放射影像学相比，HR ABI-CT 图像提供了更好的低对比度可视性。在乳房 X 线摄影术上无法分辨和重叠的细小癌结构可以看到，并可以与组织病理学结果相匹配。在乳房 X 线摄影术中，平均腺体剂量小于 1 mGy，在 CT 和 ABI-CT 中为 12-13 mGy。体外乳腺癌的良好可视性表明，当辐射剂量进一步降低且紧凑的同步辐射源可用时，HR ABI-CT 可能在未来作为当前乳房诊断的辅助手段甚至替代手段具有重要作用。
