甲状腺乳头状癌的独特生长模式，类似于腺样囊性癌。

Unique growth pattern in papillary carcinoma of the thyroid gland mimicking adenoid cystic carcinoma.

机构信息

Department of Pathology & Laboratory Medicine, University of Pennsylvania Medical Center, 6 Founders Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA.

出版信息

Endocr Pathol. 2011 Dec;22(4):200-5. doi: 10.1007/s12022-011-9174-7.

DOI:10.1007/s12022-011-9174-7

PMID:21863325

Abstract

We report here three cases of papillary thyroid carcinoma (PTC) with hyaline globules as seen in adenoid cystic carcinoma of the salivary glands. This unique growth pattern was seen in two cases of columnar cell and one case of cribriform morular variant of PTC. Fine-needle aspiration was performed in two cases. By immunohistochemistry, all cases demonstrated expression of TTF-1 and thyroglobulin confirming follicular cell derivation. It is important to be aware of this unusual growth pattern in thyroid carcinomas; immunohistochemistry is warranted for rendering accurate cytopathologic and histopathologic diagnosis.

摘要

我们在此报告 3 例甲状腺乳头状癌（PTC）病例，其表现类似于唾液腺腺样囊性癌中的透明小体。这种独特的生长模式可见于 2 例柱状细胞型和 1 例筛状滤泡型 PTC 中。其中 2 例进行了细针抽吸细胞学检查。免疫组化结果显示所有病例均表达 TTF-1 和甲状腺球蛋白，证实来源于滤泡细胞。在甲状腺癌中认识到这种不常见的生长模式很重要；进行免疫组化检查对于做出准确的细胞病理学和组织病理学诊断是必要的。