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可逆性脑血管收缩综合征:现状与未来展望。

Reversible cerebral vasoconstriction syndrome: current and future perspectives.

机构信息

Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

Expert Rev Neurother. 2011 Sep;11(9):1265-76. doi: 10.1586/ern.11.112.

DOI:10.1586/ern.11.112
PMID:21864073
Abstract

Reversible cerebral vasoconstriction syndromes (RCVS) are characterized by recurrent acute severe headaches, namely thunderclap headaches, and multifocal segmental vasoconstrictions. Interest has arisen in the definitions, clinical presentations, differential diagnoses, risk factors and complications of RCVS. This article will comprehensively review the milestone monographs and the latest research work addressing these issues. Studies that have focused on the relationship between RCVS and thunderclap headache will be detailed. We will also discuss research on the enigmatic pathophysiology and potential therapeutic approaches. Up-to-date information and challenges, undergoing studies and future research directions will be deeply probed.

摘要

可逆性脑血管收缩综合征(RCVS)的特征是反复发作的急性剧烈头痛,即霹雳头痛,以及多灶性节段性血管收缩。人们对 RCVS 的定义、临床表现、鉴别诊断、危险因素和并发症产生了兴趣。本文将全面回顾解决这些问题的里程碑式专着和最新研究工作。将详细讨论侧重于 RCVS 与霹雳头痛之间关系的研究。我们还将讨论对神秘病理生理学和潜在治疗方法的研究。将深入探讨最新信息和挑战、正在进行的研究和未来的研究方向。

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