与米诺环素胸膜固定术相关的危及生命的并发症。

Life-threatening complications related to minocycline pleurodesis.

机构信息

Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

出版信息

Ann Thorac Surg. 2011 Sep;92(3):1122-4. doi: 10.1016/j.athoracsur.2011.02.049.

DOI:10.1016/j.athoracsur.2011.02.049

PMID:21871317

Abstract

For decades, chemical pleurodesis using minocycline has been widely accepted as an effective, safe, and cheap treatment for persistent air leak after pulmonary resection. We report a case with persistent postoperative air leak that suffered from cardiorespiratory arrest just after a minocycline pleurodesis, which may be related to the aspiration of minocycline solution from a bronchopleural fistula. Therefore, we suggest a bronchoscopic examination be performed before the pleurodesis if a bronchopleural fistula is highly suspected.

摘要

数十年来，米诺环素化学性胸膜固定术已被广泛接受为治疗肺切除术后持续性气胸的有效、安全且廉价的方法。我们报告一例在米诺环素胸膜固定术后发生持续性术后气胸并伴有心肺骤停的病例，可能与支气管胸膜瘘中吸入米诺环素溶液有关。因此，如果高度怀疑存在支气管胸膜瘘，我们建议在胸膜固定术前行支气管镜检查。