Department of Psychology, Swansea University, UK.
J Neurosci Methods. 2011 Oct 15;201(2):327-32. doi: 10.1016/j.jneumeth.2011.08.016. Epub 2011 Aug 17.
The aim of this study was to establish the reliability of the observation of movement (OM) method for obtaining motor threshold (MT) in transcranial magnetic stimulation (TMS). MTs were obtained on separate days, following separate hunting procedures, for both left and right motor cortex (M1), with one or multiple estimates obtained from the same hemisphere within a single session. MTs obtained using the OM method were highly reliable and reproducible on different days (left M1: r=.98, p<.0001; right M1: r=.97, p<.0001). MTs were not influenced by the order of acquisition when two hemispheres were stimulated in the same session [F(1,22)=.12, p=.73] or by the collection of additional MTs as part of the distance-adjusted procedure [F(1,23)=.74, p=.40]. The results verify the reliability of the OM method and confirm its viability for the safe and efficient application of TMS to the left and right M1. The OM method is a reliable technique for obtaining MT and is relatively simple and quick to run. It therefore provides an effective procedure for research and clinical applications.
本研究旨在确定经颅磁刺激 (TMS) 中观察运动 (OM) 法获取运动阈值 (MT) 的可靠性。分别在不同天、采用不同的搜索程序获取左、右侧运动皮层 (M1) 的 MT 值，单次会话中可从同一半球获得一个或多个估计值。OM 法获取的 MT 值在不同天之间高度可靠且可重现（左 M1：r=.98，p<.0001；右 M1：r=.97，p<.0001）。当同一会话中刺激两个半球时，采集顺序不影响 MT 值[F(1,22)=.12，p=.73]；或者作为距离调整程序的一部分额外采集 MT 值也不影响 MT 值[F(1,23)=.74，p=.40]。结果验证了 OM 方法的可靠性，并证实其适用于安全、有效地刺激左、右侧 M1。OM 方法是一种获取 MT 的可靠技术，操作相对简单、快速。因此，它为研究和临床应用提供了一种有效的程序。
