Nimmermark Magnus O, Wang John J, Maynard Charles, Cohen Mauricio, Gilcrist Ian, Heitner John, Hudson Michael, Palmeri Sebastian, Wagner Galen S, Pahlm Olle
Lund University, Lund, Sweden.
J Electrocardiol. 2011 Sep-Oct;44(5):502-8. doi: 10.1016/j.jelectrocard.2011.06.009.
The study purpose is to determine whether numeric and/or graphic ST measurements added to the display of the 12-lead electrocardiogram (ECG) would influence cardiologists' decision to provide myocardial reperfusion therapy. Twenty ECGs with borderline ST-segment deviation during elective percutaneous coronary intervention and 10 controls before balloon inflation were included. Only 5 of the 20 ECGs during coronary balloon occlusion met the 2007 American Heart Association guidelines for ST-elevation myocardial infarction (STEMI). Fifteen cardiologists read 4 sets of these ECGs as the basis for a "yes/no" reperfusion therapy decision. Sets 1 and 4 were the same 12-lead ECGs alone. Set 2 also included numeric ST-segment measurements, and set 3 included both numeric and graphically displayed ST measurements ("ST Maps"). The mean (range) positive reperfusion decisions were 10.6 (2-15), 11.4 (1-19), 9.7 (2-14), and 10.7 (1-15) for sets 1 to 4, respectively. The accuracies of the observers for the 5 STEMI ECGs were 67%, 69%, and 77% for the standard format, the ST numeric format, and the ST graphic format, respectively. The improved detection rate (77% vs 67%) with addition of both numeric and graphic displays did achieve statistical significance (P < .025). The corresponding specificities for the 10 control ECGs were 85%, 79%, and 89%, respectively. In conclusion, a wide variation of reperfusion decisions was observed among clinical cardiologists, and their decisions were not altered by adding ST deviation measurements in numeric and/or graphic displays. Acute coronary occlusion detection rate was low for ECGs meeting STEMI criteria, and this was improved by adding ST-segment measurements in numeric and graphic forms. These results merit further study of the clinical value of this technique for improved acute coronary occlusion treatment decision support.
本研究的目的是确定在12导联心电图(ECG)显示中添加数字和/或图形ST段测量值是否会影响心脏病专家提供心肌再灌注治疗的决策。纳入了20份在择期经皮冠状动脉介入治疗期间ST段有临界偏差的心电图以及10份球囊扩张前的对照心电图。在冠状动脉球囊闭塞期间的20份心电图中,只有5份符合2007年美国心脏协会ST段抬高型心肌梗死(STEMI)指南。15位心脏病专家阅读这4组心电图,作为做出“是/否”再灌注治疗决策的依据。第1组和第4组仅为相同的12导联心电图。第2组还包括数字ST段测量值,第3组包括数字和图形显示的ST测量值(“ST图”)。第1组至第4组的平均(范围)阳性再灌注决策分别为10.6(2 - 15)、11.4(1 - 19)、9.7(2 - 14)和10.7(1 - 15)。对于5份STEMI心电图,标准格式、ST数字格式和ST图形格式的观察者准确率分别为67%、69%和77%。添加数字和图形显示后的检测率提高(77%对67%)确实具有统计学意义(P < 0.025)。对于10份对照心电图,相应的特异性分别为85%、79%和89%。总之,临床心脏病专家之间的再灌注决策存在很大差异,并且在数字和/或图形显示中添加ST偏差测量值并未改变他们的决策。符合STEMI标准的心电图急性冠状动脉闭塞检测率较低,通过添加数字和图形形式的ST段测量值可使其得到改善。这些结果值得进一步研究该技术在改善急性冠状动脉闭塞治疗决策支持方面的临床价值。