Yamamoto Hiroshi, Yamamoto Fumio, Tanaka Fuminobu, Motokawa Mamika, Shiroto Keisuke, Yamaura Gembu, Ishibashi Kazuyuki
Department of Cardiovascular Surgery, Akita University School of Medicine, Akita, Akita, Japan.
Ann Thorac Cardiovasc Surg. 2011;17(4):422-7. doi: 10.5761/atcs.cr.10.01586.
Acute aortic occlusion is a rare but catastrophic pathology with high mortality even after revascularization. We describe four patients who underwent thrombectomy or bypass surgery for acute aortic occlusion with concomitant internal iliac artery occlusion. Two patients (82- and 75-year-old men), who had insufficient reperfusion of bilateral internal iliac arteries after treatment (thrombectomy alone and axillobifemoral bypass, respectively), died on postoperative day three of uncontrollable hyperkalemia and multiple organ failure, respectively (mortality: 50%). The third patient (74-year-old man), in whom the left internal iliac artery was reperfused after an axillobifemoral bypass, underwent right lower limb amputation but survived. The fourth patient (63-year-old man) with sufficient internal iliac artery reperfusion bilaterally after aortobifemoral and right internal iliac artery reconstruction, had an uneventful postoperative course. Elevated creatine phosphokinase and myoglobinuria levels were observed in all four patients but were notably higher in the two patients with no reperfusion in either of the internal iliac arteries. Our results suggest that reperfusion of one or more internal iliac arteries may be a crucial factor in reducing mortality in revascularization treatment of acute aortic occlusion with concomitant internal iliac artery occlusion.
急性主动脉闭塞是一种罕见但灾难性的病理状况,即便在血管再通术后死亡率仍很高。我们描述了4例因急性主动脉闭塞伴髂内动脉闭塞而接受血栓切除术或旁路手术的患者。2例患者(分别为82岁和75岁男性),治疗后(分别为单纯血栓切除术和腋双股旁路手术)双侧髂内动脉再灌注不足,分别于术后第3天死于无法控制的高钾血症和多器官功能衰竭(死亡率:50%)。第3例患者(74岁男性),在腋双股旁路手术后左髂内动脉再通,接受了右下肢截肢但存活。第4例患者(63岁男性),在腹双股和右髂内动脉重建术后双侧髂内动脉再灌注充分,术后病程顺利。所有4例患者均观察到肌酸磷酸激酶升高和肌红蛋白尿水平升高,但在双侧髂内动脉均无再灌注的2例患者中明显更高。我们的结果表明,一条或多条髂内动脉的再灌注可能是降低急性主动脉闭塞伴髂内动脉闭塞的血管再通治疗死亡率的关键因素。