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[结直肠癌腹膜癌转移:细胞减灭术与腹腔热灌注化疗]

[Peritoneal carcinomatosis of colorectal cancer: cytoreductive surgery and hyperthermic intraperitoneal chemotherapy].

作者信息

Königsrainer I, Beckert S, Brücher B, Zieker D, Königsrainer A

机构信息

Allgemein, Viszeral- und Transplantationschiurgie, Universitätsklinik Tübingen.

出版信息

Dtsch Med Wochenschr. 2011 Sep;136(36):1811-4. doi: 10.1055/s-0031-1286108. Epub 2011 Aug 31.

Abstract

Peritoneal carcinomatosis caused by colorectal carcinoma is still considered as the end-stage of disease. A multi-modal therapeutic concept including maximal cytoreduction followed by intraperitoneal hyperthermic chemotherapy (HIPEC) has the potential to cure selected patients. In case of peritoneal carcinomatosis palliative systemic treatment is no longer the state of the art. This article addresses aspects of the disease, the rationale behind peritonectomy with HIPEC, and the surgical management of peritoneal carcinomatosis.

摘要

结直肠癌引起的腹膜癌仍被视为疾病的终末期。包括最大程度细胞减灭术及随后的腹腔内热化疗(HIPEC)在内的多模式治疗理念有可能治愈部分患者。对于腹膜癌患者,姑息性全身治疗已不再是当前的标准治疗方法。本文探讨了该疾病的相关方面、HIPEC辅助腹膜切除术的理论依据以及腹膜癌的手术治疗。

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