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大脑半球综合征中的神经可塑性:一个有趣的病例报告。

Neuroplasticity in hemispheric syndrome: an interesting case report.

机构信息

Department of Neurosurgery, Krishna Institute of Medical Sciences, Secunderabad, Andhra Pradesh, India.

出版信息

Neurol India. 2011 Jul-Aug;59(4):601-4. doi: 10.4103/0028-3886.84346.

Abstract

Functional hemispherectomy is an accepted treatment in hemispherical intractable epilepsy syndromes. We report a patient who had functional hemispherectomy for intractable seizures secondary to right hemispheric cortical dysplasia. Preoperatively, the patient had mild left hemiparesis and functional magnetic resonance imaging (fMRI) showed bilateral motor function lateralization to normal left hemisphere. The patient remains seizure free at 1-year follow-up, with no deterioration of motor power on left side. This report reviews physiology of neural plasticity for motor function lateralization and also reliability of fMRI in determining the functional shift.

摘要

功能性大脑半球切除术是半球性难治性癫痫综合征的一种可接受的治疗方法。我们报告了一例因右侧大脑半球皮质发育不良继发难治性癫痫而行功能性大脑半球切除术的患者。术前,患者有轻度左侧偏瘫,功能磁共振成像(fMRI)显示双侧运动功能向正常左侧大脑半球偏侧化。患者在 1 年随访时无癫痫发作,左侧运动功能无恶化。本报告回顾了运动功能偏侧化的神经可塑性生理学以及 fMRI 确定功能转移的可靠性。

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