肝细胞癌：慢性乙型病毒性肝炎和慢性丙型病毒性肝炎患者的临床及影像学表现

Hepatocellular carcinoma: clinical and radiological findings in patients with chronic B viral hepatitis and chronic C viral hepatitis.

作者信息

Kim Kyung Eun, Park Mi-Suk, Bentley-Hibbert Stuart, Baek Song-Ee, Kim Young Chul, Kim Myeong-Jin, Kim Ki Whang, Auh Yong H

机构信息

Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Abdom Imaging. 2012 Aug;37(4):591-4. doi: 10.1007/s00261-011-9799-5.

DOI:10.1007/s00261-011-9799-5

PMID:21910010

Abstract

AIM

To compare clinical and radiological findings of newly diagnosed hepatocellular carcinomas (HCCs) in patients with chronic hepatitis B virus (HBV) and chronic hepatitis C virus (HCV) infections.

MATERIALS AND METHODS

Dynamic contrast-enhanced CT images in 532 patients with newly diagnosed HCC were retrospectively reviewed. Of these patients, 418 had chronic HBV infections and 114 had chronic HCV infections. The number, size, shape (nodular vs. non-nodular) and enhancement pattern (typical vs. atypical) of hepatic lesions were assessed. The presence of portal vein thrombosis and bile duct invasion were determined.

RESULTS

The mean age of the HBV group (54.31 [range 27-85], median 54) was younger than that of the HCV group (64.21 [range 30-86], median 64) (P < 0.001). Lesions in patients with HBV were more likely to be multifocal (>5; P < 0.001); larger than 5 cm (P = 0.023); non-nodular shape (P < 0.001); atypical enhancement pattern (P = 0.047), association with portal vein thrombosis (P = 0.004); association with bile duct invasion (P < 0.001).

CONCLUSIONS

Clinical and radiological findings of HCC differ between patients with HBV and HCV infections.

摘要

目的

比较慢性乙型肝炎病毒（HBV）感染患者和慢性丙型肝炎病毒（HCV）感染患者新诊断肝细胞癌（HCC）的临床和影像学表现。

材料与方法

回顾性分析532例新诊断HCC患者的动态对比增强CT图像。其中，418例为慢性HBV感染，114例为慢性HCV感染。评估肝脏病变的数量、大小、形态（结节状与非结节状）和强化方式（典型与非典型）。确定门静脉血栓形成和胆管侵犯的情况。

结果

HBV组的平均年龄（54.31[范围27 - 85]，中位数54）低于HCV组（64.21[范围30 - 86]，中位数64）（P < 0.001）。HBV感染患者的病变更易为多灶性（>5个；P < 0.001）；大于5 cm（P = 0.023）；非结节状形态（P < 0.001）；非典型强化方式（P = 0.047）；与门静脉血栓形成相关（P = 0.004）；与胆管侵犯相关（P < 0.001）。