Karabulut Ahmet, Cakmak Mahmut, Uzunlar Bulent, Teskin Onder, Bilici Ahmet
Department of Cardiology, Istanbul Medicine Hospital, Hoca Ahmet Yesevi Cad. No: 149, 34203, Istanbul, Turkey.
Heart Vessels. 2012 Nov;27(6):585-93. doi: 10.1007/s00380-011-0188-3. Epub 2011 Sep 17.
The aim of this study was to demonstrate an assessment of left internal mammary artery (LIMA) patency and anatomy by standard left ventriculography, and to define a proposal for predicting LIMA function according to left ventriculography outcome. A total of 335 patients with an indication of coronary angiography were included. Standard coronary angiography and left ventriculography were performed initially. Visualization of LIMA occurred in the late phase of ventriculography and the LIMA visualization frame rate was counted for each patient. Then selective LIMA angiography was performed and LIMA diameter, LIMA course and anatomy, and subclavian artery anatomy were noted. Finally, the results of left ventriculography and LIMA angiography were compared by statistical analysis. During left ventriculography, LIMA was visualized in 96.4% of the patients. The mean LIMA visualization frame rate was 53.8 ± 17.7 and the mean LIMA diameter was 2.60 ± 0.36 mm. There was a strong correlation between LIMA visualization frame rate and LIMA diameter, LIMA course, and also asymptomatic subclavian artery disease (P < 0.001). Regression analysis showed that LIMA visualization frame rate is the major independent determinant for LIMA diameter prediction (P < 0.001); LIMA diameter, LIMA course, proximal LIMA side branch, and subclavian artery disease are the major predictors of LIMA visualization on left ventriculography (P < 0.001). LIMA patency and anatomy can be evaluated accurately with a simple method using left ventriculography. Besides direct visualization of LIMA, the visualization frame rate may constitute a reliable parameter for assessing LIMA function. A LIMA visualization frame rate of less than 50 is associated with a healthy and well-sized LIMA.
本研究的目的是通过标准左心室造影评估左乳内动脉(LIMA)的通畅情况和解剖结构,并根据左心室造影结果提出预测LIMA功能的方案。共纳入335例有冠状动脉造影指征的患者。最初进行标准冠状动脉造影和左心室造影。在心室造影后期观察LIMA的显影情况,并计算每位患者的LIMA显影帧率。然后进行选择性LIMA造影,记录LIMA直径、LIMA走行及解剖结构以及锁骨下动脉解剖结构。最后,通过统计分析比较左心室造影和LIMA造影的结果。在左心室造影过程中,96.4%的患者LIMA显影。LIMA平均显影帧率为53.8±17.7,LIMA平均直径为2.60±0.36mm。LIMA显影帧率与LIMA直径、LIMA走行以及无症状锁骨下动脉疾病之间存在强相关性(P<0.001)。回归分析显示,LIMA显影帧率是预测LIMA直径的主要独立决定因素(P<0.001);LIMA直径、LIMA走行、LIMA近端侧支以及锁骨下动脉疾病是左心室造影时LIMA显影的主要预测因素(P<0.001)。使用左心室造影的简单方法可准确评估LIMA的通畅情况和解剖结构。除了直接观察LIMA外,显影帧率可能是评估LIMA功能的可靠参数。LIMA显影帧率小于50与健康且大小合适的LIMA相关。