Sykora K W, Weiss R A, Ellsworth R M, McCormick B
Department of Pediatrics, New York Hospital/Cornell University Medical Center, New York.
Pediatrician. 1990;17(3):163-72.
The most common ocular and orbital tumors presenting in infancy, childhood and adolescence are presented and discussed in this review. It has been prepared specifically for the clinical pediatrician and focuses on the clinical recognition of ophthalmic neoplasms, their diagnostic evaluation employing the use of advanced imaging techniques, biopsy when indicated and extent of disease workup. In addition, current treatment modalities are discussed. Ocular tumors addressed include: retinoblastoma, capillary hemangioma, lymphangioma, dermoid and epidermoid cysts, teratoma, glioma, astrocytic hamartoma, neurofibroma, rhabdomyosarcoma and fibrous tumors. Two aggressive and potentially fatal tumors, rhabdomyosarcoma and retinoblastoma, are presented in detail. In addition, the ocular tumors associated with the phakomatoses (von Hippel-Lindau, tuberous sclerosis and neurofibromatosis) are reviewed.
本综述介绍并讨论了婴儿期、儿童期和青少年期最常见的眼部和眼眶肿瘤。它是专门为临床儿科医生编写的,重点在于眼科肿瘤的临床识别、使用先进成像技术进行诊断评估、必要时进行活检以及疾病检查的范围。此外,还讨论了当前的治疗方式。涉及的眼部肿瘤包括:视网膜母细胞瘤、毛细血管瘤、淋巴管瘤、皮样和表皮样囊肿、畸胎瘤、胶质瘤、星形细胞错构瘤、神经纤维瘤、横纹肌肉瘤和纤维瘤。详细介绍了两种侵袭性且可能致命的肿瘤——横纹肌肉瘤和视网膜母细胞瘤。此外,还综述了与错构瘤病(冯·希佩尔-林道病、结节性硬化症和神经纤维瘤病)相关的眼部肿瘤。