Sato H, Borsari R, Yajima E K, Ninomiya T, Saito C S, Kumagai C A K
Hospital Nipo-Brasileiro, Sāo Paulo, Brazil.
Eur J Gynaecol Oncol. 2011;32(4):455-6.
A rare case of increasing CA 125 and CA 19-9 levels increasing in a woman with adenomyoma is described.
A 39-year-old nullipara woman with CA 125 = 1,796 U/ml and CA 19-9 = 177 U/ml was submitted to abdominal and pelvic MRI, gastric endoscopy, colonoscopy, hysteroscopy, pelvic Doppler and PET scan. None of the exams revealed any apparent malignant disease.
Six months of gonadotropin releasing hormone agonist treatment reduced CA 125 and CA 19-9 levels. However, after contraceptive pill use the markers were again elevated, and a laparoscopic hysterectomy was performed, and normal CA 125 and CA 19-9 levels were achieved.
Adenomyoma may be associated with high levels of CA 125 and CA 19-9.