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骨质疏松症概述:从遗传学角度到临床应用。

An overview of osteoporosis: from genetics to clinics.

机构信息

Endocrinology and Metabolic Disorders, Università degli Studi di Firenze, and Metabolic Bone Disease Department, A.O.U. "Careggi", Firenze, Italy.

出版信息

Aging Clin Exp Res. 2011 Apr;23(2 Suppl):3-5.

Abstract

Osteoporosis is the most frequent metabolic bone disease and the one which mostly benefited from the knowledge of bone metabolism, both in terms of diagnosis and therapy. In the future, pharmacogenomics will optimize therapy response by customization on the basis of genotype, improving efficacy, and limiting the onset of side effects.

摘要

骨质疏松症是最常见的代谢性骨病,也是从骨代谢知识中获益最多的疾病,无论是在诊断还是治疗方面。在未来,药物基因组学将通过基于基因型的定制来优化治疗反应,提高疗效,并限制副作用的发生。

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