Clavel F, Paoletti C
INSERM U287, Institut Gustave Roussy, France.
Rev Epidemiol Sante Publique. 1990;38(2):133-8.
The harmful effect of tobacco on health is well known. To help smokers to stop smoking, a study was designed in 1987 to assess the efficacy of two treatments and the advantage of combining them. The treatments, nicotine chewing gum and acupuncture, were randomly allocated. The 996 subjects required are now included. The characteristics of the participants, the number of nicotine gums used as well as the need for a cigarette are described. Cessation rates in the four groups, one month after the beginning of the treatment, differed significantly (p less than 5%). The efficacy of acupuncture was not shown (abstinence rates of 22 and 23% for the active and placebo groups respectively), whereas the efficacy of nicotine gum was (26 and 19% for the active and placebo groups respectively). The interest of the association of the two treatments was not observed.
烟草对健康的有害影响众所周知。为帮助吸烟者戒烟，1987年设计了一项研究，以评估两种治疗方法的疗效以及联合使用的优势。这两种治疗方法，即尼古丁口香糖和针灸，是随机分配的。目前已纳入所需的996名受试者。描述了参与者的特征、使用尼古丁口香糖的数量以及对香烟的需求。治疗开始一个月后，四组的戒烟率有显著差异（p小于5%）。未显示针灸的疗效（活性组和安慰剂组的戒烟率分别为22%和23%），而尼古丁口香糖的疗效则显示出来（活性组和安慰剂组分别为26%和19%）。未观察到两种治疗联合使用的益处。
