Borlot Felippe, da Paz José Albino, Casella Erasmo Barbante, Marques-Dias Maria Joaquina
Department of Neurology, Children's Institute, Sao Paulo University, Sao Paulo, Brazil.
J Pediatr Neurosci. 2011 Jan;6(1):48-51. doi: 10.4103/1817-1745.84408.
Acute disseminated encephalomyelitis (ADEM) is an inflammatory immune-mediated disorder which is more common in pediatric patients. The clinical setting is characterized by a rapid onset of encephalopathy and multifocal neurological features. Acute hemorrhagic encephalomyelitis (AHEM) is considered a rare form of ADEM. This report shows a 2-year-old patient who presented with the classical features of ADEM and after 8 weeks developed severe neurological worsening. The second magnetic resonance image (MRI) showed hemorrhagic lesions. Differences in prognosis between ADEM and AHEM justify the investigation of AHEM whenever a patient has neurological recrudescence in a known patient of ADEM.
急性播散性脑脊髓炎（ADEM）是一种炎症性免疫介导的疾病，在儿科患者中更为常见。其临床特征为脑病迅速起病和多灶性神经功能特征。急性出血性脑脊髓炎（AHEM）被认为是ADEM的一种罕见形式。本报告展示了一名2岁患者，其表现出ADEM的典型特征，8周后出现严重的神经功能恶化。第二次磁共振成像（MRI）显示有出血性病变。ADEM和AHEM在预后上的差异表明，对于已知患有ADEM的患者，一旦出现神经功能复发，就有必要对AHEM进行调查。
