Tomkins Oren, Ben-Zion Itay, Moore Daniel B, Helveston Eugene E
Department of Ophthalmology, Bnai Zion Medical Center, Haifa, Israel.
Arch Ophthalmol. 2011 Oct;129(10):1293-7. doi: 10.1001/archophthalmol.2011.268.
To evaluate the etiologies, management, and outcomes of pediatric cataracts in a rural sub-Saharan African setting.
A retrospective, consecutive case series of patients presenting to a tertiary referral center in southern Ethiopia during a 13-month period. All patients underwent clinical examination, were diagnosed as having cataract on the basis of standard clinical assessment, and immediately underwent surgical management. Visual acuity results were grossly divided into ambulatory and nonambulatory vision according to patient age and cooperation.
Ninety-one eyes of 73 consecutive patients (57 boys and 16 girls) were included in the study. The mean (SEM) age at diagnosis was 7.1 (0.5) years (range, 0.5-15 years). Fifty-five patients had unilateral cataract and 18 had bilateral cataract. Cataracts were categorized according to the etiologic cause: congenital (n = 50), traumatic (n = 33), congenital glaucoma-related (n = 3), partially absorbed cataracts (n = 3), and congenital rubella infections (n = 2). At presentation, visual acuity ranged from 6/60 to light perception, with 13 eyes (14%) having ambulatory vision (better than hand motion). The mean postoperative visual acuity was significantly improved, ranging from light perception to 6/9. Seventy-five eyes (82%) achieved ambulatory vision. Of the 61 eyes with an implanted intraocular lens, 56 (92%) reached ambulatory visual acuity following surgery. This was significantly greater than preoperative visual acuity results (P < .001).
The underlying cause and management of pediatric cataracts in the developing world can differ significantly from that commonly reported in the literature. The effects of appropriate intervention on both visual outcome and associated survival statistics may be profound.
评估撒哈拉以南非洲农村地区小儿白内障的病因、治疗及预后。
对埃塞俄比亚南部一家三级转诊中心在13个月期间连续收治的患者进行回顾性病例系列研究。所有患者均接受临床检查,根据标准临床评估被诊断为白内障,并立即接受手术治疗。根据患者年龄和配合程度,将视力结果大致分为可走动视力和不可走动视力。
本研究纳入了73例连续患者(57例男孩和16例女孩)的91只眼。诊断时的平均(标准误)年龄为7.1(0.5)岁(范围0.5 - 15岁)。55例患者为单侧白内障,18例为双侧白内障。白内障根据病因分类:先天性(n = 50)、外伤性(n = 33)、先天性青光眼相关(n = 3)、部分吸收性白内障(n = 3)和先天性风疹感染(n = 2)。就诊时,视力范围为6/60至光感,13只眼(14%)具有可走动视力(优于手动)。术后平均视力显著提高,范围从光感至6/9。75只眼(82%)达到可走动视力。在61只植入人工晶状体的眼中,56只(92%)术后达到可走动视力。这显著优于术前视力结果(P < .001)。
发展中国家小儿白内障的潜在病因和治疗方法可能与文献中通常报道的有显著差异。适当干预对视力预后和相关生存统计数据的影响可能很大。