Department of Neurology, Medical College of Wisconsin and Froedtert Hospital, Milwaukee, Wisconsin, USA.
J Neurointerv Surg. 2009 Dec;1(2):142-5. doi: 10.1136/jnis.2009.001040. Epub 2009 Oct 30.
We present a rare complication of trans-sphenoidal adenectomy (TSA) for pituitary macroadenoma: carotid cavernous fistula (CCF) that was treated with endovascular therapy. The incidence of internal carotid artery (ICA) injury following TSA is 1% and may spontaneously heal by packing and rarely manifest as symptomatic CCF/aneurysm. Treatment of post-TSA CCF may be challenging due to the breach of nasal floor and may be prone to recurrence.
PRESENTATION/INTERVENTION: Uncontrolled intra-operative bleeding during a TSA led to an emergent angiogram to show slow-flow left CCF. Due to clinical deterioration with nasal bleeding, angiography was repeated after 4 h; the fistula had transformed into high flow with significant increase in size, and was therefore embolized using stent-assisted coiling. The fistula recanalized in a month with massive epistaxis and was re-treated using a covered stent graft.
This case represents several unique learning points: (1) CCF as a complication of TSA due to close anatomical proximity; (2) the role of endovascular management post-TSA complication; (3) stent-assisted coil embolization of high-flow fistula with moderate ICA laceration; (4) recanalization of CCF causing massive epistaxis; (5) rare use of covered stent graft stent in distal intracranial circulation maintaining integrity and patency of ICA; (6) long-term results after covered stent graft with no in-stent restenosis.
我们报告了经蝶窦腺瘤切除术(TSA)治疗垂体大腺瘤罕见的并发症:颈动脉海绵窦瘘(CCF),该并发症采用了血管内治疗。TSA 后颈内动脉(ICA)损伤的发生率为 1%,可通过填塞自行愈合,很少表现为症状性 CCF/动脉瘤。由于经蝶窦入路破坏了鼻底,治疗 TSA 后 CCF 可能具有挑战性,且易于复发。
表现/干预:在 TSA 过程中出现无法控制的术中出血,紧急进行血管造影以显示左侧 CCF 慢血流。由于伴有鼻出血的临床恶化,4 小时后再次进行血管造影;瘘已转变为高流量,大小显著增加,因此使用支架辅助弹簧圈栓塞进行治疗。瘘在一个月内再通,导致大量鼻出血,并再次使用带膜支架治疗。
该病例有几个独特的学习要点:(1)由于解剖位置接近,CCF 是 TSA 的并发症;(2)TSA 后并发症的血管内治疗作用;(3)中等 ICA 撕裂的高流量瘘的支架辅助弹簧圈栓塞;(4)CCF 再通导致大量鼻出血;(5)在颅内远端循环中使用带膜支架很少见,可保持 ICA 的完整性和通畅性;(6)带膜支架后长期无支架内再狭窄。