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[性禁欲是染色体异常病因中的一个因素吗?]

[Is sexual abstinence a factor in the etiology of chromosome abnormalities?].

作者信息

Pellestor F, Sèle B

机构信息

Laboratoire de Cytogénétique et de Biologie de la Reproduction, Faculté de Médecine de Grenoble, La Tronche.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1990;19(4):421-5.

PMID:2199562
Abstract

Some epidemiological and experimental data in mouse have suggested that there could exist a relationship between sexual abstinence duration and occurrence of chromosomal disorders. In order to determine whether sexual abstinence exerts an effect on the incidence of chromosomal abnormalities in Human, sperm chromosome complements of 4 men were analyzed after fusion with golden hamster eggs. The period of abstinence ranged from 2 days to 15 days. Seven hundred and seventy five karyotypes were obtained. The overall frequency of abnormalities was 9.4% that is not different from controls. There was no correlation between the length of the sexual abstinence and each type of chromosomal abnormality but an indirect effect of paternal aging cannot be excluded.

摘要

一些在小鼠身上的流行病学和实验数据表明,性禁欲持续时间与染色体疾病的发生之间可能存在关联。为了确定性禁欲是否会对人类染色体异常的发生率产生影响,研究人员分析了4名男性的精子染色体组型,这些精子与金黄地鼠卵融合后进行了分析。禁欲时间从2天到15天不等。共获得了775个核型。异常的总体频率为9.4%,与对照组无差异。性禁欲时间长短与每种染色体异常类型之间没有相关性,但不能排除父亲年龄的间接影响。

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