Mejborn H
National Institute of Animal Science, Research in Fur Animals, Tjele, Denmark.
J Nutr. 1990 Aug;120(8):862-8. doi: 10.1093/jn/120.8.862.
Endogenous zinc excretion was studied in adult male mink fed experimental diets for 73 d, including a collection period from d 69 to 73. Dietary zinc levels were 2.8, 26 or 121 mg/kg wet weight. In accordance with the results of a methodological study, also reported here, the animals had an intramuscular injection of 65ZnCl2 12 d before the start of the collection period. Total fecal (endogenous + unabsorbed) zinc excretion for d 69-73 in the three groups was 2.3, 20.4 and 91.0 mg. The endogenous zinc excretion was 1.3, 2.0 and 6.4 mg, corresponding to 80.8, 10.6 and 6.4% of the zinc intake. Thus, the endogenous excretion was mainly important for the zinc homeostasis at low zinc intake, whereas at high intake the homeostasis was regulated via absorption from the digestive tract. The overall conclusion of the experiment was that mink are comparable to other species (including man) in regard to mechanisms controlling zinc homeostasis.
对成年雄性水貂进行了为期73天的实验性饮食喂养，研究其内源锌排泄情况，其中包括从第69天到第73天的收集期。日粮锌水平分别为2.8、26或121毫克/千克湿重。根据本文也报道的一项方法学研究结果，在收集期开始前12天给动物肌肉注射65ZnCl2。三组动物在第69 - 73天的粪便总锌（内源 + 未吸收）排泄量分别为2.3、20.4和91.0毫克。内源锌排泄量分别为1.3、2.0和6.4毫克，分别相当于锌摄入量的80.8%、10.6%和6.4%。因此，在低锌摄入时，内源排泄对锌稳态起主要作用，而在高锌摄入时，稳态则通过消化道吸收来调节。该实验的总体结论是，在控制锌稳态的机制方面，水貂与其他物种（包括人类）具有可比性。
