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老年血液系统恶性肿瘤患者的化疗

[Chemotherapy in elderly patients with hematological malignancies].

作者信息

Ohnishi Kazunori

机构信息

Hamamatsu University, Oncology Center, Hamamatsu, Japan.

出版信息

Gan To Kagaku Ryoho. 2011 Oct;38(10):1586-90.

Abstract

A half of patients with acute myeloid leukemia and lymphoma are older than 60 years. However, using chronological age for estimating chemotherapy-related risks is unreliable, and patients without comorbidity may be candidates for the standard therapy. For patients who have complex comorbidity or are older than 75 years, a reduced dose of chemotherapy or palliative treatment is appropriate. Molecular targeted therapy may be tolerable for elderly patients.

摘要

一半的急性髓系白血病和淋巴瘤患者年龄超过60岁。然而,用实际年龄来评估化疗相关风险并不可靠,没有合并症的患者可能适合标准治疗。对于有复杂合并症或年龄超过75岁的患者,减少化疗剂量或进行姑息治疗是合适的。分子靶向治疗对老年患者可能是可耐受的。

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