Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, 15213, USA.
Resuscitation. 2012 Apr;83(4):482-7. doi: 10.1016/j.resuscitation.2011.10.001. Epub 2011 Oct 14.
Evaluate the rate, type and severity of medication errors occurring during Medical Emergency Team (MET) care at a large, tertiary-care, academic medical center.
A prospective, observational evaluation of 50 patients that required MET care was conducted. Data on medication use were collected using a direct-observation method whereby an observer documented drug information such as drug, dose, frequency, rate of administration and administration technique. Subsequently, a team of three clinicians assessed rate, type and severity of medication errors using definitions consistent with United States Pharmacopeia MEDMARX system. Severity was assessed on a scale of minor, moderate and severe.
One hundred eighty six doses were observed for 36 different medications. A total of 296 errors were identified; of these 196 errors (66%) were inappropriate aseptic technique. Of the remaining 100 errors, 46% were prescribing errors, 28% administration technique errors, 14% mislabeling errors, 10% drug preparation errors and 2% improper dose prescribing. Examples included: (1) prescribing errors, (2) administering wrong doses, (3) mislabeling, and (4) wrong administration technique such as not flushing intravenous medication through intravenous access. The rate of medication administration errors was 1.6 errors/dose including aseptic technique and 0.5 errors/dose excluding aseptic technique. A notable portion (14%) of errors was considered at least moderate in severity.
One out of 2 doses was administered in error after errors of using inappropriate aseptic technique were excluded. There is a need for education and systematic changes to prevent medication errors during medical emergencies as an effort to avoid harm.
评估大型三级学术医疗中心医疗应急小组(MET)护理期间发生的用药错误的发生率、类型和严重程度。
对需要 MET 护理的 50 名患者进行了前瞻性、观察性评估。使用直接观察法收集用药数据,观察者记录药物信息,如药物、剂量、频率、给药速度和给药技术。随后,由三名临床医生组成的团队使用与美国药典 MEDMARX 系统一致的定义评估用药错误的发生率、类型和严重程度。严重程度按轻度、中度和重度评估。
观察了 36 种不同药物的 186 个剂量。共发现 296 个错误;其中 196 个错误(66%)为无菌技术不当。其余 100 个错误中,46%为处方错误,28%为给药技术错误,14%为标签错误,10%为药物准备错误,2%为剂量不当处方。例如:(1)处方错误,(2)给予错误剂量,(3)标签错误,(4)错误的给药技术,如未通过静脉通路冲洗静脉内药物。药物给药错误的发生率为 1.6 个错误/剂量,包括无菌技术错误和 0.5 个错误/剂量,不包括无菌技术错误。相当一部分(14%)的错误被认为至少是中度严重。
排除使用不当无菌技术的错误后,每 2 个剂量中就有 1 个给药错误。需要进行教育和系统改变,以防止医疗急救期间发生用药错误,从而避免伤害。