Ohashi S, Tsukamoto Y, Goto H, Hase S, Niwa Y, Mizutani K, Suzuki T, Ohara A, Ishihara A, Nakazawa S
Second Department of Internal Medicine, Nagoya University School of Medicine, Japan.
Nihon Shokakibyo Gakkai Zasshi. 1990 May;87(5):1146-53.
The subjects were 64 cases of gastric cancer. In all 64 cases, resected specimens (formalin fixed) were subjected to endoscopic ultrasonographic examination by the water immersion method in order to assess the horizontal spread of the invasive gastric cancer. Ultrasonographic findings were compared with the histopathological findings of resected specimens. The tumor which invaded the submucosa or deeper layers was visualized as low echogenicity region in the third layer (corresponding to the submucosa) or deeper layers. The horizontal spread of the low echogenicity region represented that of the tumor or the associated fibrosis, but not the tumor itself. In the cases showing echo patterns which were characteristic of the peptic ulceration in the tumor focus (Type II-1, II-2, UL), the horizontal spread of cancer invasion in the submucosal layer or deeper layers (L Ca) was smaller than that of low echogenicity region depicted by ultrasonography (L U). In the other (Type II-3, III, A, B) cases, L Ca was almost comparable to L U.
研究对象为64例胃癌患者。对所有64例患者的切除标本(福尔马林固定)采用水浸法进行内镜超声检查,以评估浸润性胃癌的水平扩散情况。将超声检查结果与切除标本的组织病理学结果进行比较。侵犯黏膜下层或更深层的肿瘤在第三层(对应于黏膜下层)或更深层表现为低回声区。低回声区的水平扩散代表肿瘤或相关纤维化的扩散,而非肿瘤本身的扩散。在肿瘤灶表现出消化性溃疡特征性回声模式的病例(II - 1型、II - 2型、UL型)中,黏膜下层或更深层癌浸润的水平扩散(L Ca)小于超声检查所显示的低回声区的水平扩散(L U)。在其他(II - 3型、III型、A 型、B型)病例中,L Ca与L U几乎相当。