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电视辅助胸交感神经切断术治疗原发性多汗症后的生活质量和患者满意度:138例患者的随访

Quality of life and patient satisfaction after video-assisted thoracic sympathicolysis for essential hyperhidrosis: a follow-up of 138 patients.

作者信息

Vanderhelst Eef, De Keukeleire Tom, Verbanck Sylvia, Vincken Walter, Noppen Marc

机构信息

Respiratory Division, University Hospital Brussels UZB, Brussels, Belgium.

出版信息

J Laparoendosc Adv Surg Tech A. 2011 Dec;21(10):905-9. doi: 10.1089/lap.2011.0258. Epub 2011 Oct 19.

Abstract

OBJECTIVES

Essential hyperhidrosis (EH) is defined as excessive functioning of the sudomotor sweat system. Definitive treatment of choice is video-assisted thoracoscopic sympathetic interruption. Success rates are high, but compensatory hyperhidrosis (CH) remains a troublesome side effect. The aim of this study was to document patient satisfaction and side effects at least 6 months after thoracoscopic sympathicolysis.

METHODS

Between 2001 and 2005, 246 patients underwent bilateral ablation of the sympathetic chain at the thoracic level T2, T3, and/or T4. Questionnaires using open questions and scoring systems were sent at least 6 months after procedure and were returned by 138 patients (56%).

RESULTS

From the 138 patients (56 males/82 females), 39 suffered from cranial (±facial blushing), 34 from palmar, and 34 from axillary hyperhidrosis. Thirty-one patients were treated for a combination. No conversion to open surgery or deaths occurred. For the whole group, average quality of life was 4.5±2.5 before and 8.4±1.8 after surgery (P<.001). Ninety-one percent were very satisfied (score ≥7) and 80% showed an increased quality of life of ≥2. Compensatory sweating occurred in 76% of the patients, only 6% reported this as disabling. Comparing subgroups, a significant improvement in primary complaint score was found in 90%, 94%, and 91% for the T2, T3, and T4 patients, respectively. In the T4 group, the prevalence of CH was markedly lower (53%) and none of these patients were dissatisfied.

CONCLUSION

Thoracoscopic ablation of the sympathetic chain is an effective treatment for EH; CH occurs in the majority of patients, but only rarely impairs postoperative quality of life.

摘要

目的

原发性多汗症(EH)被定义为汗腺分泌系统功能亢进。明确的首选治疗方法是电视辅助胸腔镜交感神经切断术。成功率很高,但代偿性多汗(CH)仍然是一个棘手的副作用。本研究的目的是记录胸腔镜交感神经溶解术后至少6个月患者的满意度和副作用。

方法

2001年至2005年期间,246例患者在胸段T2、T3和/或T4水平进行了双侧交感神经链消融术。术后至少6个月发送了使用开放式问题和评分系统的问卷,138例患者(56%)回复。

结果

138例患者(56例男性/82例女性)中,39例患有头部(±面部潮红)多汗症,34例患有手掌多汗症,34例患有腋窝多汗症。31例患者接受了联合治疗。未发生转为开放手术或死亡情况。对于整个组,术前平均生活质量为4.5±2.5,术后为8.4±1.8(P<0.001)。91%的患者非常满意(评分≥7),80%的患者生活质量提高≥2。76%的患者出现代偿性出汗,只有6%的患者称其致残。比较亚组,T2、T3和T4患者的主要症状评分分别有90%、94%和91%有显著改善。在T4组中,CH的发生率明显较低(53%),且这些患者均无不满。

结论

胸腔镜下交感神经链消融术是治疗EH的有效方法;大多数患者会出现CH,但很少影响术后生活质量。

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