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印度一家三级医院的眶隔前蜂窝织炎和社区获得性耐甲氧西林金黄色葡萄球菌的 9 年回顾。

Nine years' review on preseptal and orbital cellulitis and emergence of community-acquired methicillin-resistant Staphylococus aureus in a tertiary hospital in India.

机构信息

Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

出版信息

Indian J Ophthalmol. 2011 Nov-Dec;59(6):431-5. doi: 10.4103/0301-4738.86309.

DOI:10.4103/0301-4738.86309
PMID:22011486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3214412/
Abstract

CONTEXT

Preseptal cellulitis is the commonest orbital disease which frequently needs to be differentiated from orbital cellulitis. Prompt diagnosis and treatment with appropriate antibiotics can prevent vision loss and life-threatening complications of orbital cellulitis.

AIMS

To describe the clinical profile of cases with preseptal and orbital cellulitis admitted to a tertiary care hospital during a period of nine years. The causative organisms and the clinical outcome were analyzed.

SETTINGS AND DESIGN

Retrospective descriptive case study done in a tertiary care hospital in South India.

MATERIAL AND METHODS

The in-patient records of patients with preseptal and orbital cellulitis were reviewed from 1998 to 2006. The factors reviewed included ocular findings aiding in the distinction of the two clinical conditions, the duration of symptoms, the duration of hospital stay, microbiological culture report of pus or wound swab, blood culture, drugs used for treatment, the response to therapy and complications.

STATISTICAL ANALYSIS USED

Descriptive analysis.

RESULTS

One hundred and ten cases, 77 patients with preseptal cellulitis and 33 patients with orbital cellulitis were reviewed. Five percent of children and 21% of adults presented with cutaneous anthrax contributing to preseptal cellulitis. Thirty-nine percent cases with orbital cellulitis were caused by methicillin-resistant Staphylococcus aureus (MRSA).

CONCLUSIONS

This study has helped in identifying organisms which cause orbital infections, especially community-acquired MRSA. It indicates the need for modifying our empirical antimicrobial therapy, especially in orbital cellulitis.

摘要

背景

眶前蜂窝织炎是最常见的眶部疾病,常需与眶蜂窝织炎相鉴别。及时诊断和应用适当的抗生素治疗可以防止视力丧失和危及生命的眶蜂窝织炎并发症。

目的

描述在 9 年期间入住一家三级保健医院的眶前和眶蜂窝织炎患者的临床特征。分析致病生物体和临床转归。

设置和设计

在印度南部的一家三级保健医院进行的回顾性描述性病例研究。

材料和方法

回顾了 1998 年至 2006 年间眶前和眶蜂窝织炎住院患者的病历。回顾的因素包括有助于区分两种临床情况的眼部表现、症状持续时间、住院时间、脓液或伤口拭子的微生物培养报告、血培养、用于治疗的药物、治疗反应和并发症。

统计分析

描述性分析。

结果

共 110 例患者,77 例眶前蜂窝织炎和 33 例眶蜂窝织炎。5%的儿童和 21%的成人患有导致眶前蜂窝织炎的皮肤炭疽。39%的眶蜂窝织炎由耐甲氧西林金黄色葡萄球菌(MRSA)引起。

结论

本研究有助于确定引起眶部感染的生物体,特别是社区获得性 MRSA。它表明需要调整我们的经验性抗菌治疗,特别是在眶蜂窝织炎中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/4fd073b2e3af/IJO-59-431-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/4f4fc62d6467/IJO-59-431-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/da3cb268169c/IJO-59-431-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/52b8c4d24ae1/IJO-59-431-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/8af057105f3a/IJO-59-431-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/4fd073b2e3af/IJO-59-431-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/4f4fc62d6467/IJO-59-431-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/da3cb268169c/IJO-59-431-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/52b8c4d24ae1/IJO-59-431-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/8af057105f3a/IJO-59-431-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a288/3214412/4fd073b2e3af/IJO-59-431-g008.jpg

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