受教育程度、职业和社区贫困与约翰斯顿县（北卡罗来纳州）骨关节炎项目中膝骨关节炎的相关性。

Associations of educational attainment, occupation and community poverty with knee osteoarthritis in the Johnston County (North Carolina) osteoarthritis project.

机构信息

Thurston Arthritis Research Center, Department of Medicine, 3300 Thurston Building, CB # 7280, University of North Carolina, Chapel Hill, NC 27599-7330, USA.

出版信息

Arthritis Res Ther. 2011;13(5):R169. doi: 10.1186/ar3492. Epub 2011 Oct 19.

DOI:10.1186/ar3492

PMID:22011570

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3308104/

Abstract

INTRODUCTION

The purpose of this study was to examine data from the Johnston County Osteoarthritis (OA) Project for independent associations of educational attainment, occupation and community poverty with tibiofemoral knee OA.

METHODS

A cross-sectional analysis was conducted on 3,591 individuals (66% Caucasian and 34% African American). Educational attainment (< 12 years or ≥12 years), occupation (non-managerial or not), and census block group household poverty rate (< 12%, 12 to 25%, > 25%) were examined separately and together in logistic models adjusting for covariates of age, gender, race, body mass index (BMI), smoking, knee injury and occupational activity score. Outcomes were presence of radiographic knee OA (rOA), symptomatic knee OA (sxOA), bilateral rOA and bilateral sxOA.

RESULTS

When all three socioeconomic status (SES) variables were analyzed simultaneously, low educational attainment was significantly associated with rOA (odds ratio (OR) = 1.44, 95% confidence interval (CI) 1.20, 1.73), bilateral rOA (OR = 1.43, 95% CI 1.13, 1.81), and sxOA (OR = 1.66, 95% CI 1.34, 2.06), after adjusting for covariates. Independently, living in a community of high household poverty rate was associated with rOA (OR = 1.83, 95% CI 1.43, 2.36), bilateral rOA (OR = 1.56, 95% CI 1.12, 2.16), and sxOA (OR = 1.36, 95% CI 1.00, 1.83). Occupation had no significant independent association beyond educational attainment and community poverty.

CONCLUSIONS

Both educational attainment and community SES were independently associated with knee OA after adjusting for primary risk factors for knee OA.

摘要

简介

本研究旨在探讨约翰斯顿县骨关节炎（OA）项目的数据，以研究受教育程度、职业和社区贫困与胫股膝关节 OA 的独立关联。

方法

对 3591 名个体（66%为白种人，34%为非裔美国人）进行横断面分析。分别和综合使用受教育程度（<12 年或≥12 年）、职业（非管理或非管理）和普查街区组家庭贫困率（<12%、12%至 25%、>25%）在调整年龄、性别、种族、体重指数（BMI）、吸烟、膝关节损伤和职业活动评分等协变量的逻辑模型中进行检查。结果为存在放射学膝关节 OA（rOA）、症状性膝关节 OA（sxOA）、双侧 rOA 和双侧 sxOA。

结果

当同时分析所有三个社会经济地位（SES）变量时，低教育程度与 rOA（比值比（OR）=1.44，95%置信区间（CI）1.20，1.73）、双侧 rOA（OR=1.43，95%CI 1.13，1.81）和 sxOA（OR=1.66，95%CI 1.34，2.06）显著相关，调整协变量后。独立地，生活在高家庭贫困率的社区与 rOA（OR=1.83，95%CI 1.43，2.36）、双侧 rOA（OR=1.56，95%CI 1.12，2.16）和 sxOA（OR=1.36，95%CI 1.00，1.83）相关。职业除了受教育程度和社区贫困之外，与膝关节 OA 没有显著的独立关联。