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围手术期药物引起的临床改变。

Clinical modifications induced by drugs during the perioperative period.

机构信息

University Hospital, Ancona, Italy.

出版信息

Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3 Suppl):S75-82. doi: 10.1177/03946320110240s311.

Abstract

Total intravenous anesthesia (TIVA) can be defined as a technique in which general anesthesia is induced and maintained using only intravenous agents. TIVA has become more popular in recent times because of the pharmacokinetic and pharmacodynamic properties of propofol, the availability of short acting synthetic opioids, and the development of delivery systems. Significant differences in anatomy and physiology in adults and children and special needs of younger patients have important consequences on many aspects of anesthesia. Airway and respiratory complications are the most common causes of morbidity during general anesthesia in children. Knowledge of the functional anatomy of airways in children forms the basis in the understanding of the pathological conditions that may occur.

摘要

全凭静脉麻醉(TIVA)可以定义为一种仅使用静脉药物诱导和维持全身麻醉的技术。由于丙泊酚的药代动力学和药效学特性、短效合成阿片类药物的可用性以及输送系统的发展,TIVA 在最近变得更加流行。成人和儿童解剖和生理学的显著差异以及年轻患者的特殊需求对麻醉的许多方面都有重要影响。气道和呼吸并发症是儿童全身麻醉期间发病率最常见的原因。了解儿童气道的功能解剖结构是理解可能发生的病理状况的基础。

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