Transplantation. 2012 Jan 15;93(1):17-21. doi: 10.1097/TP.0b013e318236cd1a.
Cryptococcosis is a significant opportunistic mycoses in organ transplant recipients. Topical developments in the field in the past few years have highlighted important issues and at the same time raised new questions regarding the management of this yeast. These include, for example, management of pretransplant cryptococcosis during transplant candidacy and timing of transplant in these instances; potential for donor transmission of cryptococcosis in light of recent fatal transmissions; and prevention and treatment of Cryptococcus-associated immune reconstitution syndrome. Discussed herein are challenges posed by these issues and evidence-based data to optimize the management of posttransplant cryptococcosis.
隐球菌病是器官移植受者中一种重要的机会性真菌感染。过去几年中，该领域的一些新进展突出了一些重要问题，同时也对这种酵母菌的治疗提出了新的问题。例如，在进行移植候选评估和这些情况下的移植时机时，如何管理移植前的隐球菌病；鉴于最近致命传播事件，供体传播隐球菌病的可能性；以及预防和治疗与隐球菌相关的免疫重建综合征。本文讨论了这些问题带来的挑战以及基于证据的数据，以优化移植后隐球菌病的管理。
