Clinique ORL, pôle TCCR, hôpital Michallon, boulevard de La-Chantourne, 38700 La-Tronche, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2011 Nov;128(5):248-52. doi: 10.1016/j.anorl.2010.12.011. Epub 2011 Oct 20.
Foreign body aspiration is a serious condition during childhood that requires prompt management to avoid complications and irreversible lung injury. Rigid bronchoscopy under general anaesthesia is the procedure of choice for removal of aspirated foreign bodies, but it can be associated with serious complications. The positive diagnosis can sometimes be challenging except in the case of radiopaque or obstructive foreign bodies, due to the low sensitivity and specificity of clinical history and physical examination.
The aim of this review is to evaluate the various investigations in children with suspected foreign body aspiration, in order to reduce the negative rigid bronchoscopy rate.
Review of the literature based on Medline data between 1980 and 2010.
Chest radiography during inspiration and expiration, often performed as the first-line radiographic investigation, has a low sensitivity and specificity. In the absence of a radiopaque foreign body, obstructive emphysema is the most specific radiographic sign. Airway fluoroscopy can complete chest radiography when radiographic signs are nonspecific. Flexible bronchoscopy is the most sensitive and most specific examination, but is not always available, as it must be performed in the operating room or with resuscitation equipment at hand. This procedure should be performed when foreign body aspiration is suspected in the absence of typical clinical and radiological signs. It can decrease the number of negative rigid bronchoscopies. Several studies suggest that chest CT is also a very sensitive examination in this indication.
The sensitivity and specificity of chest CT for the diagnosis of bronchial foreign body must be validated by a prospective study. A national multicentre study is currently underway to determine whether CT can replace flexible bronchoscopy when the diagnosis of bronchial foreign body is uncertain.
异物吸入是儿童期的一种严重情况,需要及时处理,以避免并发症和不可逆转的肺损伤。全身麻醉下硬性支气管镜检查是取出吸入性异物的首选方法,但可能会引起严重的并发症。除了不透射线或阻塞性异物外,由于临床病史和体格检查的敏感性和特异性较低,阳性诊断有时具有挑战性。
本综述旨在评估疑似异物吸入的儿童的各种检查,以降低硬性支气管镜检查的阴性率。
根据 1980 年至 2010 年 Medline 数据进行文献复习。
吸气和呼气时的胸部 X 线摄影,通常作为一线放射学检查,其敏感性和特异性较低。在没有不透射线的异物的情况下,阻塞性气肿是最特异的放射学征象。气道荧光透视术可以在放射学征象不典型时补充胸部 X 线摄影。软性支气管镜检查是最敏感和最特异的检查,但并非总是可用,因为它必须在手术室或手头备有复苏设备的情况下进行。在没有典型的临床和放射学征象时,怀疑异物吸入时应进行该检查。它可以减少阴性硬性支气管镜检查的数量。几项研究表明,在该适应证中,胸部 CT 也是一种非常敏感的检查。
需要前瞻性研究来验证胸部 CT 对支气管异物诊断的敏感性和特异性。目前正在进行一项全国性多中心研究,以确定在支气管异物诊断不确定时 CT 是否可以替代软性支气管镜检查。