(E)-1-(Pyridin-2-yl)-3-(3,4,5-trimeth-oxy-phen-yl)prop-2-en-1-one.

In the title heteroaryl chalcone derivative, C(17)H(17)NO(4), the dihedral angle between the pyridine and benzene rings is 10.82 (5)°. The two meth-oxy groups at the meta positions are essentially coplanar with the attached benzene rings [C-O-C-C torsion angles = -0.97 (14) and 179.47 (9)°], whereas the meth-oxy group at the para position is twisted from the attached ring with a C-O-C-C torsion angle of -104.48 (11)°. A C-H⋯O close contact involving two of the meth-oxy groups generates an S(6) ring motif. In the crystal, mol-ecules are linked by weak C-H⋯O inter-actions into columns along the b axis.