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[节段性肾动脉分支血栓性动脉瘤。诊断与治疗方法]

[Thrombosed aneurysm of a segmental renal artery branch. Diagnostic and therapeutic approach].

作者信息

Fornia Samanta, Campobasso Davide, Cerasi Dario, Ferretti Stefania, Meli Silvia, Moretti Matteo, Cortellini Pietro

机构信息

U.O. Urologia Azienda Ospedaliero-Universitaria di Parma, V. Gramsci 13, Parma, Italy.

出版信息

Urologia. 2011 Oct;78 Suppl 18:39-44. doi: 10.5301/RU.2011.8770.

Abstract

INTRODUCTION

We present the case of a 37-year-old man with a thrombosed aneurysm of a segmental branch of the left renal artery, which was diagnosed after a radiological investigation for colic-like pain, and treated conservatively with endovascular approach.

MATERIALS AND METHODS

After repeated episodes of colic-like pain in his left side with normal ultrasound of the urinary tract, A.R. (37 years old) undergoes a CT urogram of the abdomen, which shows a complete thrombosis of the middle third of the left renal artery, which is associated with hypoperfusion of the lower middle third of the kidney with suspected ischemia of the lower pole. In confirmation of the previous clinical scenario, we proceed with a urgent angiography, which identifies a pseudo-aneurysm, partially thrombosed, of the segmental branch of the left renal artery at the lower middle pole. During the hospitalization, the clinical picture is complicated by an unstable arterial hypertension associated with headache and nausea. A renal scintigraphy confirms a severe impairment of the renal function mainly at the level of the middle third of the lower left kidney. The total glomerular filtration rate sec. Gates was equal to 64.3 mL/min with a percentage breakdown of the global renal function of 28% to the right and 72% to the left. The location of the vascular defect argues for endovascular intervention in the attempt to preserve the remaining renal parenchyma. We proceed with a standard angiography with selective access to the left renal artery with a catheter via femoral artery Cobra 5Fx80 TERUSMO cm. The tortuosity of the thrombus and the angle of the aneurysm site prevent, despite several attempts, the passage of the guide wire for a possible stenting and fibrinolysis. We opt for the placement of 5 spirals at the aneurysm (Boston Soft GDC-10 SR 360 7mm x 15cm), in order to preserve the residual parenchyma, excluding the aneurysmal artery at risk of rupture and extent of the thrombus.

RESULTS

Immediately after the procedure, the clinical picture remained stable with complete remission of painful symptoms and with a good blood pressure control. At about 6 months, the renal scintigraphy shows a filtered global impairment of 70%, 30% for the left kidney, a slight improvement over the previous controls. The blood pressure remains within the limits with amlodipine 5 mg.

CONCLUSIONS

Renal artery aneurysms are uncommon and occur in approximately 0.09% of the general population. The etiopathogenesis at a young age is often dysplastic in nature and the diagnosis is made incidentally or during evaluation of related symptoms, being asymptomatic until they become complicated. Their treatment is proposed to prevent complications such as rupture or thrombosis. Given the extreme variability of presentation, the surgical technique, traditional or endoscopic, is at the surgeon's discretion. In our case, we opted for a conservative approach since the degree of renal parenchyma impairment and the patient's hemodynamic condition allowed to.

摘要

引言

我们报告一例37岁男性,其左肾动脉节段分支存在血栓形成的动脉瘤,该病例在因绞痛样疼痛进行放射学检查后确诊,并采用血管内介入方法进行保守治疗。

材料与方法

在左侧反复出现绞痛样疼痛且尿路超声检查正常后,37岁的A.R.接受了腹部CT尿路造影,结果显示左肾动脉中三分之一完全血栓形成,伴有肾下中三分之一灌注不足,怀疑下极缺血。为确认先前的临床情况,我们进行了紧急血管造影,发现左肾动脉下中极节段分支有一个部分血栓形成的假性动脉瘤。住院期间,临床情况因不稳定的动脉高血压伴头痛和恶心而复杂化。肾闪烁显像证实主要在左肾下三分之一中部水平肾功能严重受损。总肾小球滤过率(秒.盖茨)等于64.3毫升/分钟,右肾占全球肾功能的28%,左肾占72%。血管缺陷的位置表明应进行血管内介入以试图保留剩余的肾实质。我们通过股动脉经Cobra 5Fx80 TERUSMO cm导管对左肾动脉进行选择性标准血管造影。尽管多次尝试,但血栓的迂曲和动脉瘤部位的角度阻碍了导丝通过,无法进行可能的支架置入和纤维蛋白溶解。我们选择在动脉瘤处放置5个螺旋(波士顿软GDC - 10 SR 360 7mm x 15cm)以保留残余实质,排除有破裂风险的动脉瘤动脉和血栓范围。

结果

术后即刻,临床情况保持稳定,疼痛症状完全缓解,血压控制良好。大约6个月时,肾闪烁显像显示滤过总体损伤为70%,左肾为30%,较之前检查略有改善。使用5毫克氨氯地平后血压保持在正常范围内。

结论

肾动脉动脉瘤并不常见,在普通人群中的发生率约为0.09%。年轻时的病因发病机制通常本质上是发育异常的,诊断通常是偶然做出的,或在评估相关症状时做出,在出现并发症之前通常无症状。建议对其进行治疗以预防诸如破裂或血栓形成等并发症。鉴于临床表现的极端变异性,手术技术,无论是传统的还是内镜的,由外科医生自行决定。在我们的病例中,由于肾实质损伤程度和患者的血流动力学状况允许采用保守方法,我们选择了保守治疗。

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