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植物中的基质金属蛋白酶:简要概述。

Matrix metalloproteinases in plants: a brief overview.

机构信息

Department of Chemistry and Umeå Plant Science Centre, Umeå University, 90187 Umeå, Sweden.

出版信息

Physiol Plant. 2012 May;145(1):196-202. doi: 10.1111/j.1399-3054.2011.01544.x. Epub 2011 Dec 15.

Abstract

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases belonging to the metzincin clan. MMPs have been characterized in detail in mammals, and they have been shown to play key roles in many physiological and pathological processes. Plant MMP-like proteases exist, but relatively few have been characterized. It has been speculated that plant MMPs are involved in remodeling of the plant extracellular matrix during growth, development and stress response. However, the precise functions and physiological substrates in higher plants remain to be determined. In this brief overview, we summarize the current knowledge of MMPs in higher plants and algae.

摘要

基质金属蛋白酶(MMPs)是一类锌依赖性内肽酶,属于金属蛋白酶家族。MMPs 在哺乳动物中已被详细描述,它们被证明在许多生理和病理过程中发挥关键作用。植物 MMP 样蛋白酶存在,但已鉴定的相对较少。有人推测,植物 MMPs 参与了生长、发育和应激反应过程中植物细胞外基质的重塑。然而,高等植物中 MMP 的精确功能和生理底物仍有待确定。在这篇简要综述中,我们总结了高等植物和藻类中 MMP 的最新知识。

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