Palmer Julia, Jivraj Shehnaaz, Galimberti Andrea, Paterson Mike
Royal Hallamshire Hospital, Gynaecology, Glossop Road, Sheffield, S10 2HL, UK.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.04.2009.1809. Epub 2009 Nov 18.
The diagnosis of ovarian carcinoma in pregnancy is rare (incidence of 0.018-0.073/1000 pregnancies). Its rarity is reflected by a paucity of cases reported in the literature. The present report concerns a case of advanced serous ovarian carcinoma in a full-term pregnancy. This was an incidental finding discovered during an emergency caesarean section for presumed fetal distress. The majority of ovarian carcinomas diagnosed in pregnancy present at early stages, are associated with a good prognosis and are non-epithelial type tumours. Advanced epithelial ovarian carcinoma diagnosed in pregnancy however is associated with a poor prognosis. Case reporting should certainly contain detailed information on clinicopathological variables and treatment regimens. Longer-term maternal and neonatal outcomes are more difficult to substantiate in case reporting. The authors therefore feel that data centralisation would be beneficial in identifying optimal management strategies in these rare tumours and in other malignant tumours diagnosed and treated during pregnancy.
妊娠期卵巢癌的诊断较为罕见(发病率为0.018 - 0.073/1000次妊娠)。文献中报道的病例较少,这反映了其罕见性。本报告涉及一例足月妊娠合并晚期浆液性卵巢癌的病例。这是在因疑似胎儿窘迫而行急诊剖宫产时偶然发现的。妊娠期诊断出的大多数卵巢癌处于早期阶段,预后良好,且为非上皮型肿瘤。然而,妊娠期诊断出的晚期上皮性卵巢癌预后较差。病例报告当然应包含有关临床病理变量和治疗方案的详细信息。在病例报告中更难证实长期的母婴结局。因此,作者认为数据集中化将有助于确定这些罕见肿瘤以及妊娠期诊断和治疗的其他恶性肿瘤的最佳管理策略。