Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin, China.
J Biomed Mater Res B Appl Biomater. 2012 Jan;100(1):185-96. doi: 10.1002/jbm.b.31937. Epub 2011 Nov 21.
A series of titanium-silver-iron ternary alloys have been prepared in this study, and their feasibility as dental materials has been evaluated by the microstructural examination, mechanical testing, corrosion resistance evaluation, surface analysis, and cytotoxicity tests. More and more β-Ti phase appears at room temperature and retains with the increasing of Fe content in Ti-5Ag-xFe alloy systems. The compression strength, wear resistance, and microhardness increase largely (p < 0.05) by the addition of element Fe to Ti-Ag alloy. Moreover, when comparing with commercial pure titanium (CP Ti), nobler electrochemical corrosion behavior could be obtained for Ti-5Ag-1Fe and Ti-5Ag-2.5Fe alloys in the 1% lactic acid solution (pH = 2.1) and 0.1 mol/L H(2) O(2) + 0.9% NaCl solution (pH = 4.0). The released metal ions from Ti-5Ag-xFe alloys into the simulated fluid are trace, similar to the case of CP Ti. The addition of Fe slightly decreases the corrosion resistance of Ti-5Ag alloy. All experimental Ti-5Ag-xFe alloy extracts do not present any cytotoxicity to L-929 and NIH3T3 cell lines. All in all, the combination of superior corrosion resistance and enhanced mechanical properties make Ti-5Ag-1Fe alloy and Ti-5Ag-2.5Fe alloy suitable for dental applications.
本研究制备了一系列钛-银-铁三元合金,并通过微观结构检查、力学性能测试、耐腐蚀性评估、表面分析和细胞毒性试验评估了它们作为牙科材料的可行性。在 Ti-5Ag-xFe 合金体系中,随着 Fe 含量的增加,越来越多的β-Ti 相在室温下出现并保留。通过向 Ti-Ag 合金中添加元素 Fe,压缩强度、耐磨性和显微硬度大大提高(p < 0.05)。此外,与商业纯钛(CP Ti)相比,Ti-5Ag-1Fe 和 Ti-5Ag-2.5Fe 合金在 1%乳酸溶液(pH = 2.1)和 0.1 mol/L H(2)O(2) + 0.9% NaCl 溶液(pH = 4.0)中具有更优异的电化学腐蚀行为。Ti-5Ag-xFe 合金释放到模拟液中的金属离子痕量,与 CP Ti 的情况相似。Fe 的添加略微降低了 Ti-5Ag 合金的耐腐蚀性。所有实验性 Ti-5Ag-xFe 合金浸提液对 L-929 和 NIH3T3 细胞系均无细胞毒性。总之,优异的耐腐蚀性和增强的机械性能的结合使 Ti-5Ag-1Fe 合金和 Ti-5Ag-2.5Fe 合金适用于牙科应用。