Dale Eric, Ashby Fleur, Seelam Kalyan
St Catherine's Hospital, General Adult Psychiatry, Tickhill Road, Doncaster DN4 8QN, UK.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1454. Epub 2009 Nov 24.
This case report discusses the clinical presentation and management of a patient presenting to substance misuse services reporting chewing fentanyl patches in addition to wearing them transdermally. The patient was successfully titrated onto methadone 30 mg. Only one previously reported case of an individual chewing fentanyl patches was found in the literature; no case reports were found where treatment involved titrating the patient onto methadone. The pharmacology and illicit use of fentanyl are also considered.
本病例报告讨论了一名向药物滥用服务机构求助的患者的临床表现及治疗情况,该患者除经皮使用芬太尼贴剂外,还咀嚼芬太尼贴剂。患者成功滴定至30毫克美沙酮。文献中仅发现一例关于个体咀嚼芬太尼贴剂的报道;未发现有涉及将患者滴定至美沙酮治疗的病例报告。文中还考虑了芬太尼的药理学及非法使用情况。