Food Animal Practice Rudolph, CH-6284 Sulz, Switzerland.
Reprod Biol Endocrinol. 2011 Nov 25;9:151. doi: 10.1186/1477-7827-9-151.
Synchronization programs have become standard in the dairy industry in many countries. In Switzerland, these programs are not routinely used for groups of cows, but predominantly as a therapy for individual problem cows. The objective of this study was to compare the effect of a CIDR-Select Synch and a 12-d CIDR protocol on the pregnancy rate in healthy, multiparous dairy cows in Swiss dairy farms.
Cows (N = 508) were randomly assigned to CIDR-Select Synch (N = 262) or 12-d CIDR (N = 246) protocols. Cows in the CIDR-Select Synch group received a CIDR and 2.5 ml of buserelin i.m. on d 0. On d 7, the CIDR insert was removed and 5 ml of dinoprost was administered i.m.. Cows in the 12-d CIDR group received the CIDR on d 0 and it was removed on d 12 (the routine CIDR protocol in Swiss dairies). On d 0 a milk sample for progesterone analysis was taken. Cows were inseminated upon observed estrus. Pregnancy was determined at or more than 35 days after artificial insemination. As a first step, the two groups were compared as to indication for treatment, breed, stud book, stall, pasture, and farmer's business using chi square tests or Fisher's exact test. Furthermore, groups were compared as to age, DIM, number of AI's, number of cows per farm, and yearly milk yield per cow using nonparametric ANOVA. A multiple logistic model was used to relate the success of the protocols to all of the available factors; in particular treatment (CIDR-Select Synch/12-d CIDR), milk progesterone value, age, DIM, previous treatment of the uterus, previous gynecological treatment, and number of preceding inseminations.
The pregnancy rate was higher in cows following the CIDR-Select Synch compared to the 12-d CIDR protocol (50.4% vs. 22.4%; P < 0.0001).
The CIDR-Select Synch protocol may be highly recommended for multiparous dairy cows. The reduced time span of the progesterone insert decreased the number of days open, improved the pregnancy rate compared to the 12-d CIDR protocol and the cows did not to have to be handled more often.
同步程序已成为许多国家奶牛养殖业的标准。在瑞士，这些程序通常不适用于牛群，而是主要用于治疗个别有问题的奶牛。本研究的目的是比较 CIDR-Select Synch 和 12 天 CIDR 方案对瑞士奶牛场健康经产奶牛妊娠率的影响。
将奶牛（N=508）随机分为 CIDR-Select Synch 组（N=262）或 12 天 CIDR 组（N=246）。CIDR-Select Synch 组奶牛在第 0 天接受 CIDR 和 2.5ml 布舍瑞林肌内注射。第 7 天，取出 CIDR 插入物，肌内注射 5ml 地诺前列酮。12 天 CIDR 组奶牛在第 0 天接受 CIDR，第 12 天取出（瑞士奶牛场常规 CIDR 方案）。第 0 天取牛奶样本进行孕激素分析。奶牛在观察到发情时进行授精。人工授精后 35 天以上进行妊娠诊断。首先，使用卡方检验或 Fisher 确切检验比较两组的治疗指征、品种、种畜登记簿、牛舍、牧场和农民的业务。此外，还使用非参数 ANOVA 比较了两组的年龄、DIM、授精次数、每农场牛数和每头奶牛的年产奶量。使用多元逻辑模型将方案的成功率与所有可用因素相关联，特别是治疗（CIDR-Select Synch/12 天 CIDR）、牛奶孕激素值、年龄、DIM、子宫先前治疗、先前妇科治疗和先前授精次数。
CIDR-Select Synch 组奶牛的妊娠率高于 12 天 CIDR 方案组（50.4% vs. 22.4%；P<0.0001）。
CIDR-Select Synch 方案可能非常适合经产奶牛。孕激素插入物的时间跨度缩短，降低了开放天数，与 12 天 CIDR 方案相比，提高了妊娠率，而且奶牛不需要更频繁地处理。
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