Pennartz C, Schrader H, Ritter P R, Tannapfel A, Schmidt W E, Meier J J
Medizinische Klinik I, St. Josef Hospital, Klinikum der Ruhr-Universität Bochum, Bochum, Deutschland.
Internist (Berl). 2012 Jan;53(1):88-92. doi: 10.1007/s00108-011-2908-2.
Although liver damage is a relatively rare adverse effect of oral anticoagulation with phenprocoumon, acute liver failure can be a serious treatment-associated complication. In this contribution, a patient with drug-induced liver failure during oral anticoagulation with phenprocoumon is presented. This case illustrates the need for close laboratory monitoring and suggests that phenrocoumon-induced liver damage should be considered along with other common complications of this treatment.
尽管使用苯丙香豆素进行口服抗凝治疗时肝损伤是一种相对罕见的不良反应,但急性肝衰竭可能是一种严重的治疗相关并发症。本文介绍了一名在使用苯丙香豆素进行口服抗凝治疗期间发生药物性肝衰竭的患者。该病例说明了密切实验室监测的必要性,并表明应将苯丙香豆素引起的肝损伤与该治疗的其他常见并发症一并考虑。