Runyon Bruce Allen
Department of Internal Medicine, Division of Gastroenterology/Hepatology, Loma Linda University Medical Center, 11234 Anderson Street, Room 1556, Loma Linda, CA 92354, USA.
Int J Hepatol. 2011;2011:801983. doi: 10.4061/2011/801983. Epub 2011 Oct 26.
Many people who have cirrhosis are undiagnosed. The diagnosis may not become evident until they develop multiorgan failure after an invasive procedure. Patients with cirrhosis are unusually fragile and can be easily harmed and even set into a fatal down-spiral by seemingly innocuous treatments including medications and invasive procedures. There is much confusion regarding the care of these patients. For example, what medications can be used safely to treat pain, what sedatives are safe and effective, which medications are to be avoided, what diet should be prescribed, and which invasive procedures are safe. This paper provides the author's advice regarding clues to the presence of cirrhosis and the dos and do nots in the general care of these patients, based on his 30 years of experience in a liver-failure-focused academic practice.
许多肝硬化患者未被诊断出来。直到他们在进行侵入性操作后出现多器官衰竭,诊断才会变得明显。肝硬化患者异常脆弱,看似无害的治疗措施,包括药物治疗和侵入性操作,都可能轻易对他们造成伤害,甚至使他们陷入致命的恶性循环。对于这些患者的护理存在很多困惑。例如,哪些药物可以安全地用于治疗疼痛,哪些镇静剂安全有效,哪些药物应避免使用,应规定何种饮食,以及哪些侵入性操作是安全的。本文基于作者在以肝衰竭为重点的学术实践中的30年经验,提供了关于肝硬化存在的线索以及这些患者一般护理中的注意事项的建议。