Department of Pathology, Yale University, New Haven, CT 06610, USA.
Int J Gynecol Pathol. 2012 Jan;31(1):33-7. doi: 10.1097/PGP.0b013e318224356b.
We present a case of a 40-year-old woman with a history of human immunodeficiency virus infection and a nodular, hyperkeratotic 3.5-cm vulvar mass that increased in size over a 2-month period. Histopathologic examination of the excised mass was diagnostic of chronic hypertrophic vulvar herpes simulating neoplasia. Hypertrophic vulvar herpes presents a diagnostic challenge for both pathologists and clinicians because of its unusual clinicopathologic features that mimic neoplasia and its rarity. There is therefore the need for the correct diagnosis of this entity, so that appropriate therapy can be given. The pertinent literature is reviewed and discussed.
我们报告一例 40 岁女性，人类免疫缺陷病毒感染史，外阴有一结节性角化过度性 3.5 厘米肿块，在 2 个月内逐渐增大。切除肿块的组织病理学检查诊断为慢性增生性外阴疱疹，模拟肿瘤。由于其异常的临床病理特征类似于肿瘤，且较为罕见，增生性外阴疱疹给病理学家和临床医生的诊断带来了挑战。因此，需要正确诊断该疾病，以便给予适当的治疗。我们复习并讨论了相关文献。
