Kohlmann H-W, Respondek M
Pathologe. 2012 Mar;33(2):152-6. doi: 10.1007/s00292-011-1551-y.
This case of urinary obstruction with short anamnesis illuminates the early tissue reaction to urine extravasation, especially the Tamm-Horsfall protein. The latter becomes organized in the manner of a foreign body substance and drains via ectatic renal lymph vessels and reopened lymphovenous shunts into the intrarenal venous system. Polypoid formations (thromboids) with or without vessel obliteration appear to result in a clinical course of severe renal impairment.
该例病史短的尿路梗阻病例阐明了对尿液外渗的早期组织反应,尤其是对Tamm-Horsfall蛋白的反应。后者以异物物质的方式被组织起来,并通过扩张的肾淋巴管和重新开放的淋巴静脉分流排入肾内静脉系统。伴有或不伴有血管闭塞的息肉样形成物(血栓样物)似乎导致严重肾功能损害的临床病程。