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白内障手术中角膜内皮细胞命运的改变。

The changing fate of the corneal endothelium in cataract surgery.

机构信息

Duke University Eye Center, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Curr Opin Ophthalmol. 2012 Jan;23(1):3-6. doi: 10.1097/ICU.0b013e32834e4b5f.

Abstract

PURPOSE OF REVIEW

Corneal endothelial cell loss remains a well known, undesirable side-effect of cataract surgery that may, in severe cases, negatively impact patients' postoperative visual outcomes. This article reviews the current literature and describes in detail how the degree of corneal endothelial cell loss is influenced by specific patient risk factors, as well as the arrival of newer surgical techniques and technologies.

RECENT FINDINGS

Recent studies have demonstrated a reduction in corneal endothelial cell loss after phacoemulsification with the use of viscoelastic materials and modifications in phacoemulsification technology. Some patient characteristics may predispose patients to increased endothelial cell loss during cataract surgery.

SUMMARY

Advances in surgical technique, the implementation of newer surgical technologies such as torsional ultrasound and viscoelastic devices, and aspects of patients' preexisting medical history may lead to varying degrees of endothelial cell loss after cataract surgery. Appropriately addressing these issues during the perioperative period may improve the rate of endothelial cell loss, and thus further enhance the visual outcome of patients undergoing cataract surgery.

摘要

目的综述

白内障手术会导致角膜内皮细胞丧失,这是一个众所周知的不良副作用,在严重的情况下,可能会对患者术后的视觉效果产生负面影响。本文综述了当前的文献,并详细描述了角膜内皮细胞丧失的程度如何受到特定患者风险因素以及新技术和新设备的影响。

最近的发现

最近的研究表明,在使用粘弹性物质和改进超声乳化技术后,白内障超声乳化术中角膜内皮细胞的丧失有所减少。一些患者特征可能使患者在白内障手术中更容易发生内皮细胞丢失。

总结

手术技术的进步、新手术技术(如扭转超声和粘弹性设备)的实施以及患者既往病史的某些方面都可能导致白内障手术后内皮细胞丧失程度不同。在围手术期适当解决这些问题可能会降低内皮细胞丧失的速度,从而进一步提高接受白内障手术的患者的视觉效果。

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