Center for Biomedical Imaging, Department of Radiology, New York University, School of Medicine, New York, New York, USA.
Magn Reson Med. 2012 Jan;67(1):164-74. doi: 10.1002/mrm.23004. Epub 2011 Aug 29.
Specific absorption rate management and excitation fidelity are key aspects of radiofrequency pulse design for parallel transmission at ultra-high magnetic field strength. The design of radiofrequency pulses for multiple channels is often based on the solution of regularized least-squares optimization problems for which a regularization term is typically selected to control the integrated or peak pulse waveform amplitude. Unlike single-channel transmission, the specific absorption rate of parallel transmission is significantly influenced by interferences between the electric fields associated with the individual transmission elements, which a conventional regularization term does not take into account. This work explores the effects upon specific absorption rate of incorporating experimentally measurable electric field interactions into parallel transmission pulse design. Results of numerical simulations and phantom experiments show that the global specific absorption rate during parallel transmission decreases when electric field interactions are incorporated into pulse design optimization. The results also show that knowledge of electric field interactions enables robust prediction of the net power delivered to the sample or subject by parallel radiofrequency pulses before they are played out on a scanner.
特定吸收率管理和激励保真度是超高场强下并行传输的射频脉冲设计的关键方面。多通道射频脉冲的设计通常基于正则化最小二乘优化问题的解决方案,通常选择正则化项来控制集成或峰值脉冲波形幅度。与单通道传输不同,并行传输的特定吸收率受与各个传输元件相关的电场之间干扰的显著影响,常规正则化项不考虑这种干扰。这项工作探讨了将实验可测量的电场相互作用纳入并行传输脉冲设计对特定吸收率的影响。数值模拟和体模实验的结果表明,当将电场相互作用纳入脉冲设计优化时,并行传输过程中的全局特定吸收率会降低。结果还表明,电场相互作用的知识使得能够在并行射频脉冲在扫描仪上播放之前,对样本或对象接收到的净功率进行稳健预测。