Mühlenberg L, Schade G
Hals-Nasen-Ohrenheilunde, Universitätsklinik Bonn, Bonn, Germany.
Laryngorhinootologie. 2012 Aug;91(8):500-4. doi: 10.1055/s-0031-1291330. Epub 2011 Dec 1.
In order to obtain a low-frequency specific auditory brainstem response (ABR) there are less stimuli that plege a satisfying accordance with the ABR threshold and the behavioural threshold. This study investigates the so called low-chirp-ABR as to predict a low-frequency-amblyacousia and compares it to the notched-noise-500 Hz-ABR.
We evaluated behavioural and ABR thresholds to a low-chirp respectively a 500 Hz tone presented in notched noise masking from 32 patients with a severe hearing loss at low-frequencies and 28 patients with normal hearing.
The average difference ± single standard deviation between low-chirp-ABR and behavioural threshold is 1.53 dB ± 7.68 dB in the group of patient with low-frequency hearing loss and 2.55 dB ± 5.46 dB in the group of normal hearing. On the contrary the difference between notched-noise-500 Hz- and behavioural thereshold averages 2.67 dB ± 9.29 dB (low-frequency hearing loss) respectively 8.82 dB ± 7.90 dB (normal hearing). In order to verify the equivalence between the several methods we did a equivalence test that shows that low-chip-ABR and behavioural threshold can be considered as equal to obtain a low-frequency threshold. In contrast the comparison of notched-noise-500 Hz-ABR and behavioural threshold proves no equivalence.
We detected a significant equivalence between low-chirp-ABR and pure-tone audiometric. The ABR to a low-chirp stimulus seems to be rather precise in contrast to the notched-noise-500 Hz-evoked-ABR in order to diagnose a low-frequency-hearing loss.
为了获得低频特异性听觉脑干反应(ABR),符合ABR阈值和行为阈值的刺激较少。本研究调查了所谓的低啁啾ABR以预测低频听觉减退,并将其与500Hz陷波噪声ABR进行比较。
我们评估了32例低频重度听力损失患者和28例听力正常患者在低啁啾以及500Hz纯音在陷波噪声掩蔽下的行为阈值和ABR阈值。
低频听力损失组中,低啁啾ABR与行为阈值之间的平均差异±单标准差为1.53dB±7.68dB,听力正常组为2.55dB±5.46dB。相反,500Hz陷波噪声ABR与行为阈值之间的差异在低频听力损失组平均为2.67dB±9.29dB,在听力正常组为8.82dB±7.90dB。为了验证几种方法之间的等效性,我们进行了等效性测试,结果表明低啁啾ABR和行为阈值可被视为等效以获得低频阈值。相比之下,500Hz陷波噪声ABR与行为阈值的比较未证明等效性。
我们检测到低啁啾ABR与纯音听力测定之间存在显著等效性。与500Hz陷波噪声诱发的ABR相比,低啁啾刺激的ABR在诊断低频听力损失方面似乎更为精确。