CHRU Lille, pôle de cardiologie, Lille, France.
Cardiovasc Pathol. 2012 Jul-Aug;21(4):355-7. doi: 10.1016/j.carpath.2011.10.003. Epub 2011 Dec 3.
A previously healthy 56-year-old man presented with chest pain. Echocardiography and cardiac magnetic resonance imaging revealed minimal pericardial effusion associated with an isolated myocardial mass, protruding into the left atrium. The tumor was surgically removed. Cardiac valve morphology was strictly normal. Histology revealed a well-differentiated neuroendocrine carcinoma. Positron emission tomography scan and thin-slice abdominal computed tomography demonstrated ileal tumor, without evidence of liver metastasis. Histological study of the removed ileal tumor confirmed a neuroendocrine carcinoma, and histology of liver biopsy was negative. Somatostatin analogue treatment was started. No tumoral recurrence was observed after 1 year of follow-up. In conclusion, we report an unusual presentation of neuroendocrine carcinoma, revealed by a large solitary atrial metastasis, in the absence of liver involvement or carcinoid syndrome.
一位 56 岁既往健康的男性出现胸痛。超声心动图和心脏磁共振成像显示少量心包积液伴孤立性心肌肿块,突向左心房。肿瘤被手术切除。心瓣膜形态完全正常。组织学显示分化良好的神经内分泌癌。正电子发射断层扫描和薄层腹部计算机断层扫描显示回肠肿瘤,无肝转移证据。切除回肠肿瘤的组织学研究证实为神经内分泌癌,肝活检组织学为阴性。开始使用生长抑素类似物治疗。随访 1 年后未观察到肿瘤复发。总之,我们报告了一种不常见的神经内分泌癌表现,表现为孤立性大左房转移,无肝受累或类癌综合征。