Department of Medical Imaging, Division of Vascular and Interventional Radiology, University Health Network, University of Toronto, 585 University Avenue, NCSB 1C-553, Toronto, ON, Canada.
Cardiovasc Intervent Radiol. 2012 Dec;35(6):1396-402. doi: 10.1007/s00270-011-0316-6. Epub 2011 Dec 3.
To determine the patency rates of and factors associated with increased risk of patency failure in patients with femoral vein tunneled hemodialysis catheters.
All femoral tunneled catheter insertions from 1996 to 2006 were reviewed, during which time 123 catheters were inserted. Of these, 66 were exchanges. Patients with femoral catheter failure versus those with femoral catheter patency were compared. Confounding factors, such as demographic and procedural factors, were incorporated and assessed using univariate and multivariable Cox proportional hazards regression analyses.
Mean catheter primary patency failure time was 96.3 days (SE 17.9 days). Primary patency at 30, 60, 90, and 180 days was 53.8%, 45.4%, 32.1%, and 27.1% respectively. Crude rates of risk of catheter failure did not suggest a benefit for patients receiving catheters introduced from one side versus the other, but more cephalad location of catheter tip was associated with improved patency. Multivariate analysis showed that patients whose catheters were on the left side (p = 0.009), were of increasing age at the time of insertion (p = 0.002) and that those who had diabetes (p = 0.001) were at significantly greater risk of catheter failure. The catheter infection rate was 1.4/1000 catheter days.
Patients who were of a more advanced age and had diabetes were at greater risk of femoral catheter failure, whereas those who received femoral catheters from the right side were less at risk of catheter failure.
确定股静脉隧道式血液透析导管通畅率和与通畅失败风险增加相关的因素。
回顾了 1996 年至 2006 年期间所有的股静脉隧道式导管插入术,在此期间共插入了 123 根导管。其中 66 根为导管更换术。将股静脉导管失败的患者与股静脉导管通畅的患者进行比较。采用单变量和多变量 Cox 比例风险回归分析纳入并评估混杂因素,如人口统计学和程序因素。
平均导管初次通畅失败时间为 96.3 天(SE 17.9 天)。30、60、90 和 180 天的初次通畅率分别为 53.8%、45.4%、32.1%和 27.1%。未发现导管插入术从一侧改为另一侧会增加导管失败的风险,但导管尖端位置更靠近头侧与通畅率提高相关。多变量分析显示,导管位于左侧的患者(p=0.009)、插入时年龄增长的患者(p=0.002)以及患有糖尿病的患者(p=0.001),其导管失败的风险显著增加。导管感染率为 1.4/1000 导管日。
年龄较大且患有糖尿病的患者股静脉导管失败的风险更高,而接受右侧股静脉导管的患者导管失败的风险较低。