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缺血性二尖瓣反流行二尖瓣后环血管成形术使用血管带的长期超声心动图随访:单中心十年经验。

Long-term echocardiographic follow-up after posterior mitral annuloplasty using a vascular strip for ischemic mitral regurgitation: ten-years of experience at a single center.

机构信息

Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2011 Dec;26(12):1582-90. doi: 10.3346/jkms.2011.26.12.1582. Epub 2011 Nov 29.

Abstract

Management of ischemic mitral regurgitation (MR) is challenging. The aim of this study was to investigate long-term clinical and echocardiographic results of restrictive mitral annuloplasty for ischemic MR. From 2001 through 2010, 96 patients who underwent myocardial revascularization with restrictive mitral annuloplasty using a vascular strip for ischemic MR were analyzed. Patients were stratified into two groups based on left ventricular ejection fraction (LVEF): group I, n = 50, with LVEF > 35% and group II, n = 46, with LVEF ≤ 35%. The early mortality rate was 2.1% (2/96) and the late cardiac mortality rate was 11.5% (11/96). MR grade was reduced at discharge (0.8 ± 0.7) but increased during follow-up (1.1 ± 0.8, P = 0.001). There was no intergroup difference in terms of freedom from recurrent MR ≥ moderate eight years after surgery (94.1% ± 5.7%, group I vs 87.8% ± 7.2%, group II; P = 0.575). NYHA functional class (odds ratio [OR], 2.2; P = 0.044) and early postoperative residual MR ≥ mild (OR, 25.4; P < 0.001) were independent predictors of recurrent MR. Restrictive mitral annuloplasty using a vascular strip is effective in ischemic MR. It is important to avoid early postoperative residual MR.

摘要

缺血性二尖瓣反流(MR)的管理具有挑战性。本研究旨在探讨采用血管带行限制性二尖瓣环成形术治疗缺血性 MR 的长期临床和超声心动图结果。2001 年至 2010 年,对 96 例行心肌血运重建并采用血管带行限制性二尖瓣环成形术治疗缺血性 MR 的患者进行了分析。根据左心室射血分数(LVEF)将患者分为两组:I 组,n = 50,LVEF > 35%;II 组,n = 46,LVEF ≤ 35%。早期死亡率为 2.1%(2/96),晚期心脏死亡率为 11.5%(11/96)。出院时 MR 分级降低(0.8 ± 0.7),但在随访期间增加(1.1 ± 0.8,P = 0.001)。术后 8 年,两组间复发性 MR 程度≥中度的无复发生存率无差异[94.1% ± 5.7%(I 组)与 87.8% ± 7.2%(II 组);P = 0.575]。纽约心脏病协会(NYHA)心功能分级(比值比 [OR],2.2;P = 0.044)和术后早期残余 MR ≥轻度(OR,25.4;P < 0.001)是复发性 MR 的独立预测因素。采用血管带行限制性二尖瓣环成形术治疗缺血性 MR 有效。避免术后早期残余 MR 很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e3f/3230018/ef60e73a8d12/jkms-26-1582-g001.jpg

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