Xing Yan, Sun Jiangping, Cao Weihua, Lee Liming, Guo Haoyan, Li Hui, Duan Song
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
AIDS Care. 2012;24(6):756-62. doi: 10.1080/09540121.2011.630359. Epub 2011 Dec 7.
The purpose of this study was to analyze the cost and cost-effectiveness of methadone maintenance treatment (MMT) program in Dehong prefecture, Yunnan province, China. The cost-effectiveness analysis used process data retrospectively collected from the MMT clinics in Dehong Prefecture, Yunnan Province, from July 2005 to December 2007, a 30-month period available at the time of the study. Alternative estimates of the number of HIV infections prevented were calculated using incidence rate from cohort studies and retrospective studies. Program costs were collected retrospectively following standard methods using an ingredients methodology. The cost for each participant treated in MMT clinics was about $9.1-16.7 per month and the intervention averted 8.4-87.2 HIV infections with a cost-effectiveness of US$ 2509.3-4609.3 per HIV infection averted. This research demonstrates that MMT is a cost-effective intervention for reducing HIV transmission among injecting drug users, but the coverage of MMT intervention should be matched with the designed volume of MMT clinics to make the best use of resources.
本研究旨在分析中国云南省德宏州美沙酮维持治疗(MMT)项目的成本及成本效益。成本效益分析使用了从云南省德宏州MMT诊所回顾性收集的2005年7月至2007年12月(研究时可获取的30个月期间)的过程数据。采用队列研究和回顾性研究的发病率计算预防HIV感染人数的替代估计值。按照标准方法,采用成分法回顾性收集项目成本。MMT诊所每位接受治疗参与者的每月成本约为9.1 - 16.7美元,该干预措施避免了8.4 - 87.2例HIV感染,每避免一例HIV感染的成本效益为2509.3 - 4609.3美元。本研究表明,MMT是减少注射吸毒者中HIV传播的一种具有成本效益的干预措施,但MMT干预的覆盖范围应与MMT诊所的设计规模相匹配,以充分利用资源。