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子宫腺肌瘤的局部切除术:86 例随访分析报告。

Local excision of uterine adenomyomas: a report of 86 cases with follow-up analyses.

机构信息

Department of Obstetrics and Gynecology, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu Province, PR China.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2012 Mar;161(1):84-7. doi: 10.1016/j.ejogrb.2011.11.028. Epub 2011 Dec 5.

Abstract

OBJECTIVE

To assess the outcomes of patients who underwent local excision of adenomyoma and to evaluate the effectiveness of the procedure.

STUDY DESIGN

Prospective study of 86 women undergoing local excision of symptomatic uterine adenomyoma at laparotomy. Dysmenorrhea was assessed before and after operation by questionnaire, and the average duration of follow-up was 24 months.

RESULT(S): At 6-month follow-up, all 86 patients' dysmenorrhea grades were reduced by more than 80%. With a mean follow-up of 24 (range 6-60) months, a total of 2 (2.3%) patients finally underwent hysterectomy, 1 (1.2%) received levonorgestrel-releasing intrauterine device therapy, and three patients (11.3%) were subsequently given treatment with oral pain medication alone. The mean time interval between local excision and subsequent treatment was 34 months. Two (2.3%) patients became pregnant after the local excision: one (1.2%) at 2 months after the procedure and one (1.2%) at 3 years after the local excision procedure.

CONCLUSION(S): Local excision of uterine adenomyoma remains a safe and effective minimally invasive treatment for women with symptomatic uterine adenomyoma. Local excision can effectively alleviate the dysmenorrhea of adenomyoma.

摘要

目的

评估经局部切除术治疗子宫腺肌瘤患者的结局,并评价该术式的有效性。

研究设计

对 86 例行剖腹手术局部切除有症状的子宫腺肌瘤的妇女进行前瞻性研究。通过问卷调查评估术前和术后痛经情况,平均随访时间为 24 个月。

结果

6 个月随访时,86 例患者的痛经程度均减轻 80%以上。平均随访 24(6-60)个月,共有 2 例(2.3%)患者最终行子宫切除术,1 例(1.2%)接受左炔诺孕酮宫内节育器治疗,3 例(11.3%)患者随后单独给予口服止痛药治疗。局部切除与后续治疗之间的平均时间间隔为 34 个月。2 例(2.3%)患者在局部切除后怀孕:1 例(1.2%)在手术后 2 个月,1 例(1.2%)在局部切除后 3 年。

结论

子宫腺肌瘤的局部切除术仍是治疗有症状的子宫腺肌瘤妇女的一种安全有效的微创治疗方法。局部切除术可有效缓解腺肌瘤的痛经症状。

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