胆道狭窄治疗中的测压灌注试验

Manometric perfusion test in biliary strictures treatment.

作者信息

Cerna Marie, Thomas Rohit Philip, Köcher Martin, Peregrin Jan H, Válek Vlastimil, Havlik Roman, Fronkova Sona, Kozák Jiri, Panek Jiri, Zaplatelova Jana, Bilkova Alena

机构信息

Department of Radiology, University Hospital, Olomouc, Czech Republic.

出版信息

Hepatogastroenterology. 2012 Jul-Aug;59(117):1354-8. doi: 10.5754/hge11095.

DOI:10.5754/hge11095

PMID:22155855

Abstract

BACKGROUND/AIMS: To assess the biliary manometric perfusion test (BMPT) for evaluating success in treating benign biliary strictures.

METHODOLOGY

During 2003 to 2010, 29 patients were subjected to BMPT after percutaneous balloon dilatation treatment. Intrabiliary pressure less than 20cm of water was considered the success threshold. Results of BMPT evaluation were retrospectively compared with a similar group where the standard clinical test was used for evaluating treatment success. The clinical test group included 21 patients treated for biliary strictures from 1994 to 2006.

RESULTS

The two groups were statistically similar by age and gender. The BMPT group was tested without complications and pressure inside the biliary tree was less than 20cm of water in 27 of 29 patients. Subsequently, catheters were removed from all 27. Three patients required re-interventions 13 days, 11 months and 32 months later. Kaplan-Meier survival analysis showed that the probability of biliary patency at 3 year was 82.2%. There was no significant difference between groups by this measure (log rank test, p=0.624).

CONCLUSIONS

The manometric test is an alternative for evaluating success in treating benign biliary strictures. It is simple, less time-consuming, economical, safe, effective and more comfortable for patients than the clinical test.

摘要

背景/目的：评估胆道测压灌注试验（BMPT）在评估良性胆道狭窄治疗效果方面的作用。

方法

2003年至2010年期间，29例患者在经皮气囊扩张治疗后接受了BMPT。胆道内压力低于20厘米水柱被视为成功阈值。将BMPT评估结果与使用标准临床测试评估治疗效果的类似组进行回顾性比较。临床测试组包括1994年至2006年期间接受胆道狭窄治疗的21例患者。

结果

两组在年龄和性别方面在统计学上相似。BMPT组测试无并发症，29例患者中有27例胆道内压力低于20厘米水柱。随后，所有27例患者的导管均被拔除。3例患者分别在13天、11个月和32个月后需要再次干预。Kaplan-Meier生存分析显示，3年时胆道通畅的概率为82.2%。通过该指标两组之间无显著差异（对数秩检验，p = 0.624）。