Edinburgh Napier University, School of Nursing and Midwifery and Social Care, Edinburgh, Scotland.
Stroke. 2012 Mar;43(3):857-9. doi: 10.1161/STROKEAHA.111.640821. Epub 2011 Dec 8.
We aimed to determine the frequency of dehydration, risk factors, and associations with outcomes at hospital discharge after stroke.
We linked clinical data from stroke patients in 2 prospective hospital registers with routine blood urea and creatinine results. Dehydration was defined by a blood urea-to-creatinine ratio >80.
Of 2591 patients registered, 1606 (62%) were dehydrated at some point during their admission. Independent risk factors for dehydration included older age, female gender, total anterior circulation syndrome, and prescribed diuretics (all P<0.001). Patients with dehydration were significantly more likely be dead or dependent at hospital discharge than those without (χ(2)=170.5; degrees of freedom=2; P<0.0001).
Dehydration is common and associated with poor outcomes. Further work is required to establish if these associations are causal and if preventing or treating dehydration improves outcomes.
我们旨在确定中风患者出院时脱水的频率、相关风险因素及其与结局的关系。
我们将来自 2 个前瞻性医院登记处的中风患者的临床数据与常规血尿素和肌酐结果进行了关联。通过血尿素与肌酐的比值＞80 来定义脱水。
在登记的 2591 名患者中，有 1606 名（62%）在住院期间的某个时候出现脱水。脱水的独立危险因素包括年龄较大、女性、全前循环综合征和开利尿剂（均 P＜0.001）。与无脱水的患者相比，有脱水的患者出院时死亡或依赖的可能性显著更高（χ(2)=170.5；自由度=2；P＜0.0001）。
脱水很常见，与不良结局相关。需要进一步研究以确定这些关联是否具有因果关系，以及预防或治疗脱水是否能改善结局。
Zotero 插件